Evidence map›Paper›PMID 33189500›Full record

ArticleAmerican journal of preventive medicine2021

Vaccine Delay and Its Association With Undervaccination in Children in Sub-Saharan Africa.

Cara Bess Janusz, Margaret Frye, Martin K Mutua, Abram L Wagner, Mousumi Banerjee, Matthew L Boulton

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cara Bess JanuszDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; The Global Institute for Vaccine Equity, University of Michigan, Ann Arbor, Michigan. Electronic address: cjanusz@umich.edu.
Margaret FryeDepartment of Sociology, College of Literature, Science, and the Arts, University of Michigan, Ann Arbor, Michigan.
Martin K MutuaAfrican Population and Health Research Center, Nairobi, Kenya.
Abram L WagnerDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; The Global Institute for Vaccine Equity, University of Michigan, Ann Arbor, Michigan.
Mousumi BanerjeeDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan; Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor, Michigan.
Matthew L BoultonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan; The Global Institute for Vaccine Equity, University of Michigan, Ann Arbor, Michigan; Infectious Disease Division, Department of Internal Medicine, Michigan Medicine, Ann Arbor, Michigan.

Funding

Scientific/Technical CoreP2CHD041028 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sarah A. Burgard · 2017 to 2026
$6.5M
NICHD NIH HHS P2C HD041028
6 · The paper itself

Abstract

introductionImproving the timeliness and completion of vaccination is the key to reducing under-5 childhood mortality. This study examines the prevalence of delayed vaccination for doses administered at birth and age 6 weeks, 10 weeks, 14 weeks, and 9 months and its association with undervaccination among infants in Sub-Saharan Africa.

methodsPooling data across 33 Sub-Saharan Africa countries, vaccination timing and series completion were assessed for children aged 12-35 months who were included in the immunization module of the Demographic and Health Surveys conducted between 2010 and 2019. Survey design-adjusted logistic regression modeled the likelihood of not fully completing the basic immunization schedule associated with dose-specific delays in vaccination. Data were obtained and analyzed in May 2020.

resultsAmong children with complete date records (n=70,006), the proportion of children vaccinated with delays by ≥1 month was high: 25.9% for Bacille Calmette-Guerin (at birth); 49.1% for the third dose of pentavalent combination vaccine (at 14 weeks); and 63.9% for the first dose of measles vaccines (at 9 months). Late vaccination was more common for children born to mothers with lower levels of educational attainment (p<0.001) and wealth (p<0.001). Controlling for place, time, and sociodemographics, vaccination delays at any dose were significantly associated with not completing the immunization schedule by 12 months (Bacille Calmette-Guerin: AOR=1.93, [95% CI=1.83, 2.02]; pentavalent 3: AOR=1.50 [95% CI=1.35, 1.64]; measles: AOR=3.76 [95% CI=3.37, 4.15]).

conclusionsTimely initiation of vaccination could contribute to higher rates of immunization schedule completion, improving the reach and impact of vaccination programs on child health outcomes in Sub-Saharan Africa. SUPPLEMENT INFORMATION: This article is part of a supplement entitled Global Vaccination Equity, which is sponsored by the Global Institute for Vaccine Equity at the University of Michigan School of Public Health.

Indexed as

Immunization ProgramsMeasles VaccineAfrica South of the SaharaChildFemaleHumansImmunization ScheduleInfantInfant, NewbornVaccinationMeasles Vaccine

Identifiers

PMID33189500
PMCPMC10601532

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.