ArticleIndian heart journal
Stroke in cardiac sarcoidosis: Need to worry?
Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Cerebral Infarction Diagnosed as Isolated Cardiac Sarcoidosis.NMC case report journal · 2026Article
- Internal Carotid Artery Occlusion Associated with Cardiac Sarcoidosis during the Postpartum Period Treated with Thrombectomy: A Case Report.NMC case report journal · 2025Article
- Isolated cardiac sarcoidosis presenting as transient ischemic attack.Clinical case reports · 2024Article
- Neurological Manifestations of Myocarditis.Current neurology and neuroscience reports · 2022Review
- Cardioembolic Stroke Due to Cardiac Sarcoidosis Diagnosed by Pathological Evaluation of the Retrieved Thrombus.Internal medicine (Tokyo, Japan) · 2022Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe occurrence of stroke in patients with cardiac sarcoidosis (CS) is an under-recognized entity. The objective of this study is to evaluate the clinical presentation, risk factors, etiology, temporal relationship and management of stroke in patients with CS.
methodsThe data of 111 patients with CS from the Granulomatous Myocarditis Registry was analyzed. Clinical data regarding the clinical presentation, risk factors for vascular disease, electrocardiogram, echocardiogram and
resultsAmong the 111 patients with CS, 8 patients (7.2%) had a history of ischemic stroke. Six of the eight patients with ischemic stroke were young (<50 years) without conventional risk factors for vascular disease. In five patients, stroke occurred prior to the diagnosis of CS. In all except one patient the ischemic stroke occurred in the anterior cerebral circulation. LV dysfunction was noted in all patients at the time of stroke, with the presence of an LV apical clot in four of the eight patients. Atrial fibrillation was documented in 2 patients. Two patients received thrombolysis and mechanical thrombectomy, while the others were treated with standard antiplatelets and statins. There was a significant improvement in the LV Ejection fraction (33.6 ± 15.2 to 49.1 ± 13.8%, p = 0.043) following immunosuppression. Two patients developed refractory HF and respiratory sepsis, respectively, and succumbed following prolonged ICU admissions.
conclusionsIschemic stroke in patients with CS can be attributed to a cardioembolic phenomenon. A high index of clinical suspicion is needed for early diagnosis and management of these patients.
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