Evidence map›Paper›PMID 33189150›Full record

ArticleBMC musculoskeletal disorders2020

Selective thoracolumbar/lumbar fusion for Syringomyelia-associated scoliosis: a case-control study with Lenke 5C adolescent idiopathic scoliosis.

Fan Feng, Hongxing Shen, Xiuyuan Chen, Zude Liu, Jianwei Chen, Quan Li, Lifeng Lao

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fan FengDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Hongxing ShenDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Xiuyuan ChenDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Zude LiuDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Jianwei ChenDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Quan LiDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China.
Lifeng LaoDepartment of Spine Surgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, No.160 Pujian Road, Shanghai, 200120, China. spinelao@163.com.

Funding

National Natural Science Foundation of China 81802216National Natural Science Foundation of China 81972127
6 · The paper itself

Abstract

backgroundSelective thoracolumbar/lumbar fusion technique was introduced to treat adolescent idiopathic scoliosis (AIS) patients with major thoracolumbar/lumbar curves. Theoretically, this surgical strategy could also be applied to syringomyelia patients. No previous study has specifically addressed the effectiveness of selective thoracolumbar/lumbar fusion for patients with syringomyelia-associated scoliosis. The aim of the study was to investigate the effectiveness of selective thoracolumbar/lumbar fusion for the surgical treatment of patients with syringomyelia-associated scoliosis.

methodsFrom February 2010 to September 2016, 14 syringomyelia-associated patients with major thoracolumbar/lumbar curves were retrospectively reviewed. Besides, 30 Lenke 5C AIS patients were enrolled as a control group. Posterior selective thoracolumbar/lumbar fusion was performed for both groups. Patients' demographic, operative, radiological, and quality of life data were reviewed with follow-up. Intragroup comparisons were performed for each parameter.

resultsThe two groups were matched by age, gender, curve characteristics, duration of follow-up, and all preoperative radiographic parameters except for thoracic kyphosis. After surgery, the average correction rate of the major thoracolumbar/lumbar curve was 82.2 ± 7.8% in the syringomyelia group, which was not significantly different from that of AIS group (82.5 ± 10.6%, P = 0.47). A similar improvement of unfused thoracic curve was observed between the two groups (50.1 ± 16.5% vs. 48.5 ± 26.9%, P = 0.29). During the follow-up, the correction effect of scoliosis was well maintained, without aggravation of the original neural symptoms or fresh permanent neurological deficits. Of note, the number of fusion levels was significantly larger in syringomyelia group than that in AIS group (7.6 ± 1.4 vs. 6.5 ± 1.2, P < 0.01). The average follow up was 47.6 months (36-81 months).

conclusionSimilar to AIS cases, syringomyelia-associated scoliosis can be effectively and safely corrected by selective thoracolumbar/lumbar fusion with satisfactory surgical outcomes. However, the syringomyelia group, on average, required an additional fused segment for treatment as compared to the AIS group (7.6 versus 6.5 in the AIS group).

Indexed as

KyphosisScoliosisSpinal FusionSyringomyeliaAdolescentCase-Control StudiesHumansLumbar VertebraeQuality of LifeRetrospective StudiesThoracic VertebraeTreatment OutcomeScoliosisSelective fusionSyringomyeliaThoracolumbar/lumbar

Identifiers

PMID33189150
PMCPMC7666459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.