Evidence map›Paper›PMID 33188652›Full record

ReviewEuropean journal of immunology2021

Functional and metabolic dichotomy of murine γδ T cell subsets in cancer immunity.

Noëlla Lopes, Bruno Silva-Santos

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. γδ T cells in oral diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Pooled it
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  14. Metabolic regulation of T cell development.Frontiers in immunology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Noëlla LopesInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Bruno Silva-SantosInstituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
University of Lisbon · PT

Funding

EMBO ALTF 752-2018FEDER (POR Lisboa 2020) and Fundação para a Ciência e a Tecnologia (Portugal) ALTF 752-2018"la Caixa" Foundation's Health Research Program HR18-00069"la Caixa" Foundation's Health Research Program PAC-PRECISE LISBOA-01-0145-FEDER-016394
6 · The paper itself

Abstract

γδ T cells can display a plethora of immune functions, but recent studies have highlighted their importance, in multiple disease models, as sources of the pro-inflammatory cytokines, IL-17A (IL-17), and IFN-γ. These are produced by distinct murine effector γδ T cell subsets that diverge during thymic γδ T cell development. Among the multiple roles these subsets play in peripheral tissues, a striking dichotomy has emerged at tumor sites: whereas IFN-γ

Indexed as

AnimalsCell ProliferationCytotoxicity, ImmunologicHumansInterferon-gammaInterleukin-17Intraepithelial LymphocytesMiceModels, ImmunologicalMyeloid-Derived Suppressor CellsNeoplasms, ExperimentalNeovascularization, PathologicReceptors, Antigen, T-Cell, gamma-deltaTumor MicroenvironmentIl17a protein, mouseInterferon-gammaInterleukin-17Receptors, Antigen, T-Cell, gamma-deltaIFN-γIL-17metabolismtumor immunologyγδ T cells

Identifiers

PMID33188652
PMCPMC7839746
OpenAlexW3101968882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.