Evidence map›Paper›PMID 33188573›Full record

ArticleMuscle & nerve2021

Walking activity in a large cohort of boys with Duchenne muscular dystrophy.

Donovan J Lott, Tanja Taivassalo, Claudia R Senesac, Rebecca J Willcocks, Ann M Harrington, Kirsten Zilke, Hilary Cunkle, Catherine Powers, Erika L Finanger, William D Rooney and 2 more

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Muscle & nerve, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01484678 (Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01484678 recruitingnot on this map

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

TypeobservationalSponsorUniversity of FloridaRan2020 to 2026Enrolled550ConditionsDuchenne Muscular Dystrophy, Becker Muscular Dystrophy
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Wearable sensors in paediatric neurology.Developmental medicine and child neurology · 2025
    Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Donovan J LottDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Tanja TaivassaloDepartment of Physiology and Functional Genomics, University of Florida, Gainesville, Florida, USA.
Claudia R SenesacDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Rebecca J WillcocksDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Ann M HarringtonDepartment of Physical Therapy, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Kirsten ZilkeOregon Health & Science University, Shriners Hospitals for Children, Portland, Oregon, USA.
Hilary CunkleDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Catherine PowersDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Erika L FinangerDepartment of Pediatrics, Oregon Health and Science University, Portland, Oregon, USA.
William D RooneyAdvanced Imaging Research Center, Oregon Health and Science University, Portland, Oregon, USA.
Gihan I TennekoonDepartment of Physical Therapy, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Krista VandenborneDepartment of Physical Therapy, University of Florida, College of Public Health & Health Professions, Gainesville, Florida, USA.
Florida College · USUniversity of Florida Health · USChildren's Hospital of Philadelphia · USOregon Health & Science University · USShriners Hospitals for Children - Portland · USUniversity of Florida · US

Funding

Magnetic Resonance Imaging and Biomarkers for Muscular DystropyR01AR056973 · NIAMS · UNIVERSITY OF FLORIDA · PI VANDENBORNE, KRISTA H · 2010 to 2024
$20.2M
Rehabilitation Research Career Development ProgramK12HD055929 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BROWN, DAVID A · 2007 to 2021
$11.7M
NIAMS NIH HHS R01 AR056973NICHD NIH HHS K12 HD055929
6 · The paper itself

Abstract

introductionIn this study we explored walking activity in a large cohort of boys with Duchenne muscular dystrophy (DMD).

methodsStep activity (monitored for 7 days), functional ability, and strength were quantified in ambulatory boys (5-12.9 years of age) with DMD and unaffected boys. Ambulatory status was determined 2 years later.

resultsTwo to 5 days of activity monitoring predicted weekly step activity (adjusted R DISCUSSION: Step activity for DMD is related to and predictive of functional declines, which may be useful for clinical trials.

Indexed as

ExerciseWalkingAccelerometryActivities of Daily LivingCase-Control StudiesChildChild, PreschoolCohort StudiesDisease ProgressionFunctional StatusGlucocorticoidsHumansMaleMobility LimitationMuscular Dystrophy, DuchenneGlucocorticoidsaccelerometry, daily steps, Duchenne muscular dystrophy, functional ability, physical activity, walking

Identifiers

PMID33188573
PMCPMC8314165
OpenAlexW3104928959

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.