Evidence map›Paper›PMID 33188485›Full record

ArticleActa parasitologica2021

Prevalence and Genetic Characterization of Cryptosporidium and Microsporidia Infecting Hematological Malignancy Patients.

Ujjala Ghoshal, Sonali K Kalra, Nidhi Tejan, Prabhat Ranjan, Asmita Dey, Soniya Nityanand

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In one paragraph

Article in Acta parasitologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Prevalence and Molecular Characterization ofInternational journal of microbiology · 2026
    Article
  3. Current research in parasitology & vector-borne diseases · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Identification and Subtyping ofIranian journal of parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ujjala GhoshalDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India. ujjalaghoshal@yahoo.co.in.ORCID http://orcid.org/0000-0001-9500-3949
Sonali K KalraDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India.
Nidhi TejanDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India.
Prabhat RanjanDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India.
Asmita DeyDepartment of Microbiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India.
Soniya NityanandDepartment of Haematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareili road, Lucknow, UP, 226014, India.
Sanjay Gandhi Post Graduate Institute of Medical Sciences · IN

Funding

Indian Council of Medical Research 5/3/3/3/2008‑ECD‑I
6 · The paper itself

Abstract

purposeTo evaluate the prevalence of Cryptosporidium and Microsporidia, associated risk factors and species identification in patients with haematological malignancies (HM).

methodsA total of 148 consecutive patients with HM and 101 healthy subjects were evaluated for Cryptosporidium and Microsporidia using modified Kinyoun and modified Trichrome staining. Clinical, demographic and laboratory parameters were studied. The species of Cryptosporidium and Microsporidia were studied using PCR-RFLP.

resultsOf 148 HM patients initially screened, 47 were excluded from the final analysis due to inadequate clinical records. Patients with HM [n = 101, 63 (62.4%) male] more often had Cryptosporidium than healthy subjects [n = 101, 65 (74.4%) male] [3/101 (3%) vs. 0/101 (0%), p = 0.02]. Two of 101 (2%) HM patients and none of the healthy subjects had Microsporidia (p = 0.155). Diarrhea was more prevalent in HM patients with Cryptosporidium than those without [3, 100% vs. 39/96, 40.62%; p = 0.04). Both patients infected with Microsporidia presented with persistent diarrhea and fever. Cryptosporidium hominis was identified in all the three HM patients. Enterocytozoon bieneusi was identified in one HM patient infected with Microsporidia, which was classified as genotype Ind2.

conclusionCryptosporidium and Microsporidia may infect HM patients leading to overwhelming diarrhea. The commonest species of Cryptosporidium and Microsporidia found to infect HM patients are C. hominis and E. bieneusi.

Indexed as

CryptosporidiosisCryptosporidiumEnterocytozoonHematologic NeoplasmsMicrosporidiaMicrosporidiosisFecesGenotypeHumansMalePrevalenceCryptosporidiosisDiarrheaIntestinal microsporidiosisMalignancy

Identifiers

PMID33188485
OpenAlexW3105717976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.