ArticleAnalytical and bioanalytical chemistry2021
Challenges and future directions in LC-MS-based multiclass method development for the quantification of food contaminants.
Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Isotope dilution LC-MS/MS for the quantification of ergot alkaloids: a comparative study.Analytical and bioanalytical chemistry · 2026Article
- Development of a Dispersive µSPE Method for the Determination of Pesticide Residues in Water Samples by LC-MS/MS.Molecules (Basel, Switzerland) · 2026Article
- Interfacial chemistry governs SERS detectability of trimethoprim and ketoprofen: adsorption geometry and chloride-mediated activation.RSC advances · 2025Article
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- Omics advancements towards exploring arsenic toxicity and tolerance in plants: a review.Planta · 2025Review
- Bioanalysis, Analysis, Chemistry, and Pharmacological Aspects of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors.Current topics in medicinal chemistry · 2025Review
- Enhanced Surveillance of >1100 Pesticides and Natural Toxins in Food: Harnessing the Capabilities of LC-HRMS for Reliable Identification and Quantification.Foods (Basel, Switzerland) · 2024Article
- Analysis types and quantification methods applied in UHPLC-MS metabolomics research: a tutorial.Metabolomics : Official journal of the Metabolomic Society · 2024Review
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- Covalent Organic Frameworks-Based Electrochemical Sensors for Food Safety Analysis.Biosensors · 2023Review
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- Strategic Priorities of the Scientific Plan of the European Research Infrastructure METROFOOD-RI for Promoting Metrology in Food and Nutrition.Foods (Basel, Switzerland) · 2022Review
- Acute Infectious Gastroenteritis: The Causative Agents, Omics-Based Detection of Antigens and Novel Biomarkers.Children (Basel, Switzerland) · 2021Review
- Development, validation, and application of a multi-method for the determination of mycotoxins, plant growth regulators, tropane alkaloids, and pesticides in cereals by two-dimensional liquid chromatography tandem mass spectrometry.Analytical and bioanalytical chemistry · 2021Article
- Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review.Foods (Basel, Switzerland) · 2021Review
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4 authors.
Funding
Abstract
Monitoring of food contaminants and residues has undergone a significant improvement in recent years and is now performed in an intensive manner. Achievements in the area of chromatography-mass spectrometry coupling techniques enabled the development of quantitative multi-target approaches covering several hundred analytes. Although the majority of methods are focusing on the analysis of one specific group of substances, such as pesticides, mycotoxins, or veterinary drugs, current trends are going towards the simultaneous determination of multiclass compounds from several families of contaminants and residues. This work provides an overview of relevant multiclass concepts based on LC-MS/MS and LC-HRMS instruments. Merits and shortcomings will be critically discussed based on current performance characteristics of the EU legislation system. In addition, the discussion of a recently developed multiclass approach covering >1000 substances is presented as a case study to illustrate the current developments in this area.
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