ArticleJournal of experimental botany2021
TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis.
Article in Journal of experimental botany, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Genome-wide identification and expression analysis of the PnNPR-PnTGA gene family reveal its potential role in response to biotic stresses in Panax notoginseng.BMC plant biology · 2026Article
- Unveiling the TGA gene family in Qingke (Hordeum vulgare L. var. nudum) and the role of HvnTGA2 in host-pathogen interaction.BMC plant biology · 2026Article
- miR398-SlCSD1 module participates in the SA-HJournal of advanced research · 2026Article
- Genome-wide characterization and expression profiling of theFrontiers in plant science · 2025Article
- The transcription factor TGA2 orchestrates salicylic acid signal to regulate cold-induced proline accumulation in Citrus.The Plant cell · 2024Article
- Evolution of Duplicated Glutathione Metabolic Pathway inEcology and evolution · 2024Article
- Using RNA-Seq Analysis to Select Key Genes Related to Seed Dormancy in ALS-Inhibiting ResistantPlants (Basel, Switzerland) · 2024Article
- Exogenous Cytokinin 4PU-30 Modulates the Response of Wheat and Einkorn Seedlings to Ultraviolet B Radiation.Plants (Basel, Switzerland) · 2024Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2024Article
- Reactive oxygen species- and nitric oxide-dependent regulation of ion and metal homeostasis in plants.Journal of experimental botany · 2023Article
- Arabidopsis TGA256 Transcription Factors Suppress Salicylic-Acid-Induced Sucrose Starvation.Plants (Basel, Switzerland) · 2023Article
- A mini-TGA protein modulates gene expression through heterogeneous association with transcription factors.Plant physiology · 2023Article
- Genome-wide analysis reveals regulatory mechanisms and expression patterns ofFrontiers in plant science · 2023Article
- The TGA Transcription Factors from Clade II Negatively Regulate the Salicylic Acid Accumulation in Arabidopsis.International journal of molecular sciences · 2022Article
- OsRLCK160 contributes to flavonoid accumulation and UV-B tolerance by regulating OsbZIP48 in rice.Science China. Life sciences · 2022Article
- Ran-GTP/-GDP-dependent nuclear accumulation of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 and TGACG-BINDING FACTOR2 controls salicylic acid-induced leaf senescence.Plant physiology · 2022Article
- TGA transcription factors-Structural characteristics as basis for functional variability.Frontiers in plant science · 2022Review
- A Genome-Wide Analysis ofFrontiers in genetics · 2022Article
- Transcriptomic Changes in Internode Explants of Stinging Nettle during Callogenesis.International journal of molecular sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants possess a robust metabolic network for sensing and controlling reactive oxygen species (ROS) levels upon stress conditions. Evidence shown here supports a role for TGA class II transcription factors as critical regulators of genes controlling ROS levels in the tolerance response to UV-B stress in Arabidopsis. First, tga256 mutant plants showed reduced capacity to scavenge H2O2 and restrict oxidative damage in response to UV-B, and also to methylviologen-induced photooxidative stress. The TGA2 transgene (tga256/TGA2 plants) complemented these phenotypes. Second, RNAseq followed by clustering and Gene Ontology term analyses indicate that TGA2/5/6 positively control the UV-B-induced expression of a group of genes with oxidoreductase, glutathione transferase, and glucosyltransferase activities, such as members of the glutathione S-transferase Tau subfamily (GSTU), which encodes peroxide-scavenging enzymes. Accordingly, increased glutathione peroxidase activity triggered by UV-B was impaired in tga256 mutants. Third, the function of TGA2/5/6 as transcriptional activators of GSTU genes in the UV-B response was confirmed for GSTU7, GSTU8, and GSTU25, using quantitative reverse transcription-PCR and ChIP analyses. Fourth, expression of the GSTU7 transgene complemented the UV-B-susceptible phenotype of tga256 mutant plants. Together, this evidence indicates that TGA2/5/6 factors are key regulators of the antioxidant/detoxifying response to an abiotic stress such as UV-B light overexposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.