Evidence map›Paper›PMID 33188185›Full record

ArticleNature communications2020

Associations between blood type and COVID-19 infection, intubation, and death.

Michael Zietz, Jason Zucker, Nicholas P Tatonetti

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 265 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
265citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

265 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review and meta-analysis of the susceptibility of ABO blood group to COVID-19 infection.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
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  12. Observational
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  16. Article
  17. Immunity and Coagulation in COVID-19.International journal of molecular sciences · 2024
    Review
  18. Review
  19. Article
  20. Narrative Review Explaining the Role ofInfectious disease reports · 2024
    Review

205 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael ZietzDepartment of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-0539-630X
Jason ZuckerDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Nicholas P TatonettiDepartment of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, USA. nick.tatonetti@columbia.edu.ORCID 0000-0002-2700-2597

Funding

Training in Biomedical Informatics at Columbia UniversityT15LM007079 · NLM · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NOEMIE ELHADAD, GEORGE M HRIPCSAK · 1992 to 2026
$28.9M
Precision Pharmacology and Pharmacovigilance: Leveraging AI to address drug safety knowledge gapsR35GM131905 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Nicholas P Tatonetti · 2019 to 2026
$3.3M
NIGMS NIH HHS R35 GM131905NLM NIH HHS T15 LM007079
6 · The paper itself

Abstract

The rapid global spread of the novel coronavirus SARS-CoV-2 has strained healthcare and testing resources, making the identification and prioritization of individuals most at-risk a critical challenge. Recent evidence suggests blood type may affect risk of severe COVID-19. Here, we use observational healthcare data on 14,112 individuals tested for SARS-CoV-2 with known blood type in the New York Presbyterian (NYP) hospital system to assess the association between ABO and Rh blood types and infection, intubation, and death. We find slightly increased infection prevalence among non-O types. Risk of intubation was decreased among A and increased among AB and B types, compared with type O, while risk of death was increased for type AB and decreased for types A and B. We estimate Rh-negative blood type to have a protective effect for all three outcomes. Our results add to the growing body of evidence suggesting blood type may play a role in COVID-19.

Indexed as

ABO Blood-Group SystemBetacoronavirusRh-Hr Blood-Group SystemAdultClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingHumansIntubation, IntratrachealPandemicsPneumonia, ViralPrevalenceRisk FactorsSARS-CoV-2Survival AnalysisABO Blood-Group SystemRh-Hr Blood-Group System

Identifiers

PMID33188185
PMCPMC7666188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.