Evidence map›Paper›PMID 33188066›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Cell Type-Specific Oxidative Stress Genomic Signatures in the Globus Pallidus of Dopamine-Depleted Mice.

Alyssa J Lawler, Ashley R Brown, Rachel S Bouchard, Noelle Toong, Yeonju Kim, Nitinram Velraj, Grant Fox, Michael Kleyman, Byungsoo Kang, Aryn H Gittis and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Combining Machine Learning and Multiplexed,bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. AnFrontiers in genetics · 2025
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  14. Addiction-Associated Genetic Variants Implicate Brain Cell Type- and Region-Specific Cis-Regulatory Elements in Addiction Neurobiology.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Alyssa J LawlerComputational Biology alawler@andrew.cmu.edu apfenning@cmu.edu.ORCID 0000-0002-2151-5164
Ashley R BrownComputational Biology.ORCID 0000-0002-3091-3930
Rachel S BouchardBiological Sciences.
Noelle ToongComputational Biology.
Yeonju KimComputational Biology.
Nitinram VelrajComputational Biology.
Grant FoxComputational Biology.
Michael KleymanComputational Biology.ORCID 0000-0001-9994-2652
Byungsoo KangComputational Biology.
Aryn H GittisBiological Sciences.ORCID 0000-0002-3591-5775
Andreas R PfenningComputational Biology alawler@andrew.cmu.edu apfenning@cmu.edu.ORCID 0000-0002-7390-5041
Carnegie Mellon University · USComputational Physics (United States) · US

Funding

Interpreting the regulatory mechanisms underlying the predisposition to substance use disordersDP1DA046585 · NIDA · CARNEGIE-MELLON UNIVERSITY · PI PFENNING, ANDREAS ROBERT · 2018 to 2022
$2.4M
NIDA NIH HHS DP1 DA046585
6 · The paper itself

Abstract

Neuron subtype dysfunction is a key contributor to neurologic disease circuits, but identifying associated gene regulatory pathways is complicated by the molecular complexity of the brain. For example, parvalbumin-expressing (PV

Indexed as

AnimalsCerebral CortexCorpus StriatumGlobus PallidusMiceMice, TransgenicNeuronsOxidative StressOxidopamineParkinson Disease, SecondaryOxidopamineepigenomicsglobus pallidusHif2aoxidative stressParkinson's diseaseparvalbumin

Identifiers

PMID33188066
PMCPMC7726543
OpenAlexW3101119105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.