Evidence map›Paper›PMID 33188030›Full record

ArticleScience advances2020

Nanobubble-controlled nanofluidic transport.

Jake Rabinowitz, Elizabeth Whittier, Zheng Liu, Krishna Jayant, Joachim Frank, Kenneth Shepard

Abstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Reply to Lü: Aerophilic interfaces across scales.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Navigating the unknown: Nanobubbles and the hidden complexity of aerophilic surfaces.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Charge Mapping ofAnalytical chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jake RabinowitzDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA.ORCID http://orcid.org/0000-0001-9671-6860
Elizabeth WhittierDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA.ORCID http://orcid.org/0000-0001-6320-6717
Zheng LiuDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA.
Krishna JayantDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA.ORCID http://orcid.org/0000-0003-4353-6123
Joachim FrankDepartment of Biological Sciences, Columbia University, New York, NY 10027, USA.
Kenneth ShepardDepartment of Electrical Engineering, Columbia University, New York, NY 10027, USA. shepard@ee.columbia.edu.ORCID http://orcid.org/0000-0003-0665-6775

Funding

STRUCTURE ANALYSIS OF MACROMOLECULAR ASSEMBLIESR01GM029169 · NIGMS · WADSWORTH CENTER · PI FRANK, JOACHIM · 1985 to 2019
$6.1M
Enzyme-less DNA base discrimination using solid-state nanopores with high-frequency integrated detection electronicsR01HG009189 · NHGRI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DRNDIC, MARIJA, SHEPARD, KENNETH L · 2016 to 2018
$1.2M
NHGRI NIH HHS R01 HG009189NIGMS NIH HHS R01 GM029169
6 · The paper itself

Abstract

Nanofluidic platforms offering tunable material transport are applicable in biosensing, chemical detection, and filtration. Prior studies have achieved selective and controllable ion transport through electrical, optical, or chemical gating of complex nanostructures. Here, we mechanically control nanofluidic transport using nanobubbles. When plugging nanochannels, nanobubbles rectify and occasionally enhance ionic currents in a geometry-dependent manner. These conductance effects arise from nanobubbles inducing surface-governed ion transport through interfacial electrolyte films residing between nanobubble surfaces and nanopipette walls. The nanobubbles investigated here are mechanically generated, made metastable by surface pinning, and verified with cryogenic transmission electron microscopy. Our findings are relevant to nanofluidic device engineering, three-phase interface properties, and nanopipette-based applications.

Identifiers

PMID33188030
PMCPMC7673748

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.