Evidence map›Paper›PMID 33188025›Full record

ArticleScience advances2020

Repeated gain and loss of a single gene modulates the evolution of vascular plant pathogen lifestyles.

Emile Gluck-Thaler, Aude Cerutti, Alvaro L Perez-Quintero, Jules Butchacas, Verónica Roman-Reyna, Vishnu Narayanan Madhavan, Deepak Shantharaj, Marcus V Merfa, Céline Pesce, Alain Jauneau and 16 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Meta-analysis of theMicrobial genomics · 2022
    Pooled it
  2. Article
  3. Genome Evolution in Plant Pathogenic Bacteria.Genome biology and evolution · 2026
    Review
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  16. A recently collectedMicrobial genomics · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 10 institutions in 4 countries.

Emile Gluck-ThalerDepartment of Plant Pathology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-0438-7495
Aude CeruttiLIPM, Université de Toulouse, INRAE, CNRS, Université Paul Sabatier, Castanet-Tolosan, France.ORCID 0000-0003-2838-5021
Alvaro L Perez-QuinteroAgricultural Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0003-3530-8251
Jules ButchacasDepartment of Plant Pathology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-9346-5883
Verónica Roman-ReynaDepartment of Plant Pathology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-0072-8096
Vishnu Narayanan MadhavanCSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India.ORCID 0000-0003-3970-4999
Deepak ShantharajDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.
Marcus V MerfaDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.
Céline PesceIRD, CIRAD, Université Montpellier, IPME, Montpellier, France.
Alain JauneauInstitut Fédératif de Recherche 3450, Plateforme Imagerie, Pôle de Biotechnologie Végétale, Castanet-Tolosan, France.
Taca VanchevaIRD, CIRAD, Université Montpellier, IPME, Montpellier, France.
Jillian M LangAgricultural Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0001-8890-7026
Caitilyn AllenDepartment of Plant Pathology, University of Wisconsin-Madison, Madison, WI 53706, USA.ORCID 0000-0001-5805-8000
Valerie VerdierIRD, CIRAD, Université Montpellier, IPME, Montpellier, France.ORCID 0000-0001-5425-9454
Lionel GagnevinIRD, CIRAD, Université Montpellier, IPME, Montpellier, France.ORCID 0000-0002-2943-0827
Boris SzurekIRD, CIRAD, Université Montpellier, IPME, Montpellier, France.ORCID 0000-0002-1808-7082
Gregg T BeckhamRenewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO 80401, USA.ORCID 0000-0002-3480-212X
Leonardo De La FuenteDepartment of Entomology and Plant Pathology, Auburn University, Auburn, AL 36849, USA.ORCID 0000-0002-0027-4840
Hitendra Kumar PatelCSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India.
Ramesh V SontiCSIR-Centre for Cellular and Molecular Biology, Hyderabad 500007, India.ORCID 0000-0003-4845-0601
Claude BragardEarth & Life Institute, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
Jan E LeachAgricultural Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0000-0001-7252-4397
Laurent D NoëlLIPM, Université de Toulouse, INRAE, CNRS, Université Paul Sabatier, Castanet-Tolosan, France.ORCID 0000-0002-0110-1423
Jason C SlotDepartment of Plant Pathology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-6731-3405
Ralf KoebnikIRD, CIRAD, Université Montpellier, IPME, Montpellier, France. jacobs.1080@osu.edu koebnik@gmx.de.ORCID 0000-0002-4419-0542
Jonathan M JacobsDepartment of Plant Pathology, The Ohio State University, Columbus, OH 43210, USA. jacobs.1080@osu.edu koebnik@gmx.de.ORCID 0000-0002-1553-2013
Centre de Coopération Internationale en Recherche Agronomique pour le Développement · FRThe Ohio State University · USAuburn University · USCentre for Cellular and Molecular Biology · INColorado State University · USCentre National de la Recherche Scientifique · FRInstitut d'Imagerie Biomédicale · FRNational Laboratory of the Rockies · USUCLouvain · BEUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular plant pathogens travel long distances through host veins, leading to life-threatening, systemic infections. In contrast, nonvascular pathogens remain restricted to infection sites, triggering localized symptom development. The contrasting features of vascular and nonvascular diseases suggest distinct etiologies, but the basis for each remains unclear. Here, we show that the hydrolase CbsA acts as a phenotypic switch between vascular and nonvascular plant pathogenesis.

Indexed as

XanthomonasBacteriaHydrolasesPhylogenyPlantsHydrolases

Identifiers

PMID33188025
PMCPMC7673761
OpenAlexW3100215111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.