ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2020
Premature Years of Life Lost Due to Cancer in the United States in 2017.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
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- Political determinants of US states' screening-amenable cancer stage at diagnosis and premature cancer mortality.JNCI cancer spectrum · 2025Observational
- The mortality rate and years of life lost due to cancer in a City of North of Islamic Republic of Iran during the years 2013-2021: joinpoint regression analysis.Annals of medicine and surgery (2012) · 2025Article
- Machine learning-based mortality risk assessment in first-episode bipolar disorder: a transdiagnostic external validation study.EClinicalMedicine · 2025Article
- Mortality from prostate cancer in the years 2007-2021 in North Rhine-Westphalia, Germany.BMC urology · 2024Article
- Diagnostic and Therapeutic Particularities of Symptomatic Melanoma Brain Metastases from Case Report to Literature Review.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Years of life lost due to cancer in the United Kingdom from 1988 to 2017.British journal of cancer · 2023Article
- Article
- Impact of Social Vulnerability on Comorbid Cancer and Cardiovascular Disease Mortality in the United States.JACC. CardioOncology · 2022Article
- HIV, tuberculosis, diabetes mellitus and hypertension admissions and premature mortality among adults in Uganda from 2011 to 2019: is the tide turning?Tropical medicine and health · 2022Article
- Gastric adenocarcinoma: 1-year overall survival, disability-adjusted life years, years of life lost, and prognostic factors-a single-institution experience.Frontiers in oncology · 2022Article
- Male-Female Disparities in Years of Potential Life Lost Attributable to COVID-19 in the United States: A State-by-State Analysis.medRxiv : the preprint server for health sciences · 2021Article
- Cost-Effectiveness Threshold for Healthcare: Justification and Quantification.Inquiry : a journal of medical care organization, provision and financingArticle
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Authors and funding
3 authors.
Funding
Abstract
backgroundBurden of cancer mortality is often measured by death counts or mortality rates, but potential years of life lost (PYLL) and PYLL per death may be more useful to estimate the impact of cancer-related deaths occurring at younger ages.
methodsWe used U.S. national death certificate data. A total of 45 categories of common cancers were grouped for cancer-specific calculations of PYLL and PYLL per death. PYLL was defined as the sum of the total years of life lost prior to age 75 years.
resultsThe largest number of PYLL in 2017 was due to deaths from cancers of the lung/bronchus (891,313; 20.8%), colon/rectum (409,538; 9.6%), and breast (400,643; 9.4%). Cancers with the highest PYLLs generally also caused the largest number of deaths and had the highest mortality rates, with the exception of prostate cancer (5.1% of deaths, 2.0% of PYLL). In contrast, PYLLs per death were greatest for deaths due to cancers of testis (mean = 34.0 years), bones/joints (26.4), and other endocrine sites including thymus (25.2).
conclusionsAlthough PYLLs generally reflect mortality rates, they more heavily weigh cancers that occur at younger ages. In contrast, PYLL per death, which is an average quantification of life years lost for individual patients with cancer, shows a different pattern. IMPACT: Mortality rates, PYLL, and PYLL per death are complementary measures of the burden of deaths due to cancer that should be considered in tandem to prioritize public health interventions focused on preventing premature mortality.
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