Evidence map›Paper›PMID 33187334›Full record

ArticleInternational journal of molecular sciences2020

Analysis of miR-9-5p, miR-124-3p, miR-21-5p, miR-138-5p, and miR-1-3p in Glioblastoma Cell Lines and Extracellular Vesicles.

Alja Zottel, Neja Šamec, Ana Kump, Lucija Raspor Raspor Dall'Olio, Pia Pužar Dominkuš, Rok Romih, Samo Hudoklin, Jernej Mlakar, Daniil Nikitin, Maxim Sorokin and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 45 citations in OpenAlex.

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  9. miR-21-5p Targets PIK3R1 to Regulate the NF-International journal of endocrinology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Alja ZottelMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-8587-3390
Neja ŠamecMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-1291-1931
Ana KumpMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Lucija Raspor Raspor Dall'OlioMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6293-5563
Pia Pužar DominkušMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Rok RomihInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0001-9598-3561
Samo HudoklinInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Jernej MlakarInstitute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Daniil NikitinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Maxim SorokinOncobox ltd., Moscow 121205, Russia.
Anton BuzdinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Ivana JovčevskaMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0002-0418-2986
Radovan KomelMedical Centre for Molecular Biology, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
University of Ljubljana · SIMoscow Institute of Physics and Technology · RUInstitute of Bioorganic Chemistry · RU

Funding

Interreg Interreg 2014-2020 V-A It.-Slo., Ref. No. 146Javna Agencija za Raziskovalno Dejavnost RS postdoctoral project Z3-1869Javna Agencija za Raziskovalno Dejavnost RS Research Programme Grant P1-0390Javna Agencija za Raziskovalno Dejavnost RS Research Programme Grant P3-0108Javna Agencija za Raziskovalno Dejavnost RS Young Researcher Grant to Alja Zottel
6 · The paper itself

Abstract

Glioblastoma (GBM), the most common primary brain tumor, is a complex and extremely aggressive disease. Despite recent advances in molecular biology, there is a lack of biomarkers, which would improve GBM's diagnosis, prognosis, and therapy. Here, we analyzed by qPCR the expression levels of a set of miRNAs in GBM and lower-grade glioma human tissue samples and performed a survival analysis

Indexed as

AstrocytesBiomarkers, TumorBrain NeoplasmsCell Line, TumorExtracellular VesiclesGene Expression Regulation, NeoplasticGlioblastomaHumansMicroRNAsPrognosisRNA, MessengerBiomarkers, TumorMicroRNAsRNA, MessengerbiomarkersexosomesglioblastomamiR-124-3pmiR-138-5pmiR-21-5pmiR-9-5pmiRNAsmall extracellular vesiclesvimentin

Identifiers

PMID33187334
PMCPMC7698225
OpenAlexW3103756951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.