ArticleNutrients2020
Sarcopenia Severity Based on Computed Tomography Image Analysis in Patients with Cirrhosis.
Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07667608 (Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Correlation between sarcopenia and cirrhosis: a meta-analysis.Frontiers in nutrition · 2023Pooled it
- Radiological Assessment of Sarcopenia and Its Association with Metabolic Markers in Patients with Liver Cirrhosis.Journal of clinical medicine · 2026Article
- Recompensation in Patients With Alcohol-Related Liver Disease-A Multicenter Study.Gastro hep advances · 2026Article
- Construction of a severity prediction model for hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease based on machine learning.European journal of medical research · 2025Article
- Comparing efficacy of different scoring models to predict hepatic encephalopathy after TIPS in cirrhotic patients.Annals of medicine · 2025Article
- Type II fibre atrophy and nuclear disruption in decompensated cirrhosis.JHEP reports : innovation in hepatology · 2025Article
- Review
- A sex-oriented analysis concerning skeletal muscle quantity and quality and associations to quality of life in hospitalized patients with cirrhosis.Health and quality of life outcomes · 2024Article
- Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis.BMC gastroenterology · 2024Article
- MRI paraspinous skeletal muscle enhancement: A potential imaging biomarker for assessing clinical liver cirrhosis severity.PloS one · 2024Article
- Assessing the risk factors associated with sarcopenia in patients with liver cirrhosis: a case-control study.Scientific reports · 2023Article
- Establishing a HOPE Program in a Real-life Setting: A Brazilian Case Series.Transplantation direct · 2023Article
- Osteosarcopenia in NAFLD/MAFLD: An Underappreciated Clinical Problem in Chronic Liver Disease.International journal of molecular sciences · 2023Review
- CT-based skeletal muscle loss for predicting poor survival in patients with hepatocellular carcinoma experiencing curative hepatectomy plus adjuvant transarterial chemoembolization: a preliminary retrospective study.European journal of medical research · 2022Article
- Correlation Between Bioelectrical Impedance Analysis and Chest CT-Measured Erector Spinae Muscle Area: A Cross-Sectional Study.Frontiers in endocrinology · 2022Article
- Age-specific reference values for low psoas muscle index at the L3 vertebra level in healthy populations: A multicenter study.Frontiers in nutrition · 2022Article
- Machine Learning Models for Sarcopenia Identification Based on Radiomic Features of Muscles in Computed Tomography.International journal of environmental research and public health · 2021Article
- Muscular abnormalities in liver cirrhosis.World journal of gastroenterology · 2021Review
- Use of skeletal muscle index as a predictor of short-term mortality in patients with acute-on-chronic liver failure.Scientific reports · 2021Article
- Definition of Sarcopenia in Chronic Liver Disease.Life (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Standardized sex-specific cut-offs for sarcopenia in cirrhosis are needed to identify the risk of clinical complications and to discriminate the severity of sarcopenia. We aimed to compare clinical characteristics between patients with cirrhosis categorized according to the severity of sarcopenia. Computed tomography images were taken at the 3rd lumbar vertebra from 603 patients with cirrhosis and 129 adult donors for living liver transplantation. Patients with skeletal muscle index (SMI) two standard deviations (SD) below the sex-specific mean value of young donors (18-40 years old) were categorized as having severe sarcopenia whereas patients with SMI between -1 and -2 SD of the sex-specific young adult mean values were categorized as having sarcopenia. In the cirrhosis group, 408 patients (68%) were male with the mean age of 57 ± 0.4 years, and MELD score of 14 ± 0.4. Patients were divided into three groups: severe-sarcopenic (SMI < 30 cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.