Evidence map›Paper›PMID 33187300›Full record

ArticleJournal of clinical medicine2020

Longitudinal Asthma Patterns in Italian Adult General Population Samples: Host and Environmental Risk Factors.

Sara Maio, Sandra Baldacci, Marzia Simoni, Anna Angino, Stefania La Grutta, Vito Muggeo, Salvatore Fasola, Giovanni Viegi, On Behalf Of The Agave Pisa Group

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. What Is Asthma?Journal of clinical medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sara MaioPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology (IFC), 56126 Pisa, Italy.
Sandra BaldacciPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology (IFC), 56126 Pisa, Italy.
Marzia SimoniPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology (IFC), 56126 Pisa, Italy.
Anna AnginoPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology (IFC), 56126 Pisa, Italy.
Stefania La GruttaCNR Institute for Biomedical Research and Innovation (IRIB), 90146 Palermo, Italy.
Vito MuggeoDepartment of Economics, Business and Statistics, University of Palermo, 90128 Palermo, Italy.ORCID 0000-0002-3386-4054
Salvatore FasolaCNR Institute for Biomedical Research and Innovation (IRIB), 90146 Palermo, Italy.ORCID 0000-0002-5378-5505
Giovanni ViegiPulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology (IFC), 56126 Pisa, Italy.ORCID 0000-0002-1855-4410
On Behalf Of The Agave Pisa Group
Istituto di Fisiologia Clinica · ITInstitute for Biomedical Research and Innovation · ITUniversity of Palermo · IT

Funding

Italian Electric Power Authority 'Interaction of Energy Systems with Human Health and Environment' Project (1989)Italian Medicines Agency Contract N°. FARM8YRYZC; 2010Italian National Research Council Targeted Project 'Prevention and Control Disease Factors-SP 2' (Contract N°. 91.00171.PF41; 1991)
6 · The paper itself

Abstract

backgroundAsthma patterns are not well established in epidemiological studies.

aimTo assess asthma patterns and risk factors in an adult general population sample.

methodsIn total, 452 individuals reporting asthma symptoms/diagnosis in previous surveys participated in the AGAVE survey (2011-2014). Latent transition analysis (LTA) was performed to detect baseline and 12-month follow-up asthma phenotypes and longitudinal patterns. Risk factors associated with longitudinal patterns were assessed through multinomial logistic regression.

resultsLTA detected four longitudinal patterns: persistent asthma diagnosis with symptoms, 27.2%; persistent asthma diagnosis without symptoms, 4.6%; persistent asthma symptoms without diagnosis, 44.0%; and ex -asthma, 24.1%. The longitudinal patterns were differently associated with asthma comorbidities. Persistent asthma diagnosis with symptoms showed associations with passive smoke (OR 2.64, 95% CI 1.10-6.33) and traffic exposure (OR 1.86, 95% CI 1.02-3.38), while persistent asthma symptoms (without diagnosis) with passive smoke (OR 3.28, 95% CI 1.41-7.66) and active smoke (OR 6.24, 95% CI 2.68-14.51).

conclusionsLTA identified three cross-sectional phenotypes and their four longitudinal patterns in a real-life setting. The results highlight the necessity of a careful monitoring of exposure to active/passive smoke and vehicular traffic, possible determinants of occurrence of asthma symptoms (with or without diagnosis). Such information could help affected patients and physicians in prevention and management strategies.

Indexed as

asthmacohortcomorbiditiesepidemiologylatent transition analysissmokevehicular traffic

Identifiers

PMID33187300
PMCPMC7696248
OpenAlexW3098086498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.