Evidence map›Paper›PMID 33187192›Full record

ArticleJournal of clinical medicine2020

Prognostic Value of Elevated Copeptin and High-Sensitivity Cardiac Troponin T in Patients with and without Acute Coronary Syndrome: The ConTrACS Study.

Hanna Waldsperger, Moritz Biener, Kiril M Stoyanov, Mehrshad Vafaie, Hugo A Katus, Evangelos Giannitsis, Matthias Mueller-Hennessen

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Article
  3. Prognostic tools at hospital arrival in acute myocardial infarction: copeptin and hepatocyte growth factor.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022
    Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hanna WaldspergerDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Moritz BienerDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Kiril M StoyanovDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Mehrshad VafaieDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Hugo A KatusDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Evangelos GiannitsisDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Matthias Mueller-HennessenDepartment of Internal Medicine III, Heidelberg University Hospital, 69120 Heidelberg, Germany.
University Hospital Heidelberg · DEHeidelberg University · DE

Funding

Thermo Fisher Scientific 5172015
6 · The paper itself

Abstract

aimsWe aimed to assess the prognostic role of copeptin in patients presenting to the emergency department with acute symptoms and increased high-sensitivity cardiac troponin T.

methodsA total of 3890 patients presenting with acute symptoms to the emergency department of Heidelberg University Hospital were assessed for increased hs-cTnT (>14 ng/L) from three cohorts: the Heidelberg Acute Coronary Syndrome (ACS) Registry (

resultsMedian follow-up was 1468 days in the ACS cohort and 709 days in the non-ACS cohort. Elevated copeptin levels (>10 pmol/L) were found in 1174 patients (60.0%) in the entire cohort (58.1% in ACS and 68.5% in non-ACS, respectively) and mortality rates were significantly higher than in patients with normal copeptin levels (29.0% vs. 10.7%,

conclusionCopeptin may aid in identifying patients at risk for adverse outcomes in patients with increased levels of hs-cTnT in ACS patients and in non-ACS conditions.

Indexed as

acute coronary syndromecardiac troponincopeptinemergency departmenthigh sensitivityprognosisrisk stratification

Identifiers

PMID33187192
PMCPMC7696893
OpenAlexW3099883632

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.