Evidence map›Paper›PMID 33187188›Full record

Observational studyNutrients2020

Mediterranean Personalized Diet Combined with Physical Activity Therapy for the Prevention of Cardiovascular Diseases in Italian Women.

Laura Di Renzo, Giulia Cinelli, Maria Dri, Paola Gualtieri, Alda Attinà, Claudia Leggeri, Giuseppe Cenname, Ernesto Esposito, Alberto Pujia, Gaetano Chiricolo and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  12. Observational
  13. Review
  14. Circadian Gene Variants: Effects in Overweight and Obese Pregnant Women.International journal of molecular sciences · 2024
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  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Laura Di RenzoSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-8875-6723
Giulia CinelliSchool of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-6985-3982
Maria DriDepartment of Surgical Sciences, School of Applied Medical-Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Paola GualtieriSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-1533-4276
Alda AttinàSchool of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Claudia LeggeriSchool of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Giuseppe CennameComando Generale Arma Carabinieri, Direzione di Sanità, 00197 Rome, Italy.
Ernesto EspositoDepartment of Human Policies (General Directorate) of Basilicata Region, 85100 Potenza, Italy.
Alberto PujiaDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Gaetano ChiricoloDepartment of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Chiara SalimeiDepartment of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
Antonino De LorenzoSection of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-6524-4493
University of Rome Tor Vergata · ITMinistero della Salute · ITUniversity of Basilicata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) and inflammatory risk indexes are used to calculate the exposure to morbidity. Most of them are suggested by the American College of Cardiology/American Heart Association to predict the risk of CVDs diagnosis in primary prevention, instead of treating the ongoing pathology. Prevention starts from habit changes with the prescription of diet and physical activity (PA). The aim of the study is to investigate the effectiveness of a personalized Mediterranean Diet (MD) and a PA intervention, on the risk indexes Atherogenic Index of Plasma (AIP), Lipid Accumulation Product (LAP) and Fatty Liver Index (FLI) in a population of women at risk of CVDs with different pathological conditions. After treatment, patients achieved the best results in body composition (BC) and laboratory tests. The BC analysis showed a significant reduction of total body Fat Mass (FM). CVDs risk indexes significantly decreased, except for Neutrophil/Lymphocyte (NLR) and Platelet/Lymphocyte Ratios (PLR). The reduction of the CVDs indexes associated with lipid profile was linked to both weight and FM decrease. AIP and LAP were significantly reduced when losing fat mass and body weight, respectively. A personalized MD therapy plus a PA program led to body weight loss, BC remodelling and risk indexes reduction.

Indexed as

Body CompositionDiet, MediterraneanExerciseAdultCardiovascular DiseasesFemaleHumansItalyLipidsMiddle AgedPrimary PreventionProspective StudiesRisk FactorsRisk Reduction BehaviorWeight LossLipidscardiovascular diseaseMediterranean dietnon-communicable diseaseobesityphysical activity

Identifiers

PMID33187188
PMCPMC7697155
OpenAlexW3102862502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.