Evidence map›Paper›PMID 33187165›Full record

ArticleInternational journal of molecular sciences2020

Gene Expression Profiling in Huntington's Disease: Does Comorbidity with Depressive Symptoms Matter?

Gabriela Delevati Colpo, Natalia Pessoa Rocha, Erin Furr Stimming, Antonio Lucio Teixeira

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. The pathobiology of depression in Huntington's disease: an unresolved puzzle.Journal of neural transmission (Vienna, Austria : 1996) · 2024
    Review
  3. Article
  4. A Glimpse of Molecular Biomarkers in Huntington's Disease.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gabriela Delevati ColpoNeuropsychiatry Program, Louis A Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77054, USA.
Natalia Pessoa RochaHDSA Center of Excellence at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Erin Furr StimmingHDSA Center of Excellence at The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Antonio Lucio TeixeiraNeuropsychiatry Program, Louis A Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77054, USA.ORCID 0000-0002-9621-5422
The University of Texas Health Science Center at Houston · USInstituto de Ensino e Pesquisa Santa Casa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease (HD) is an inherited neurodegenerative disease. Besides the well-characterized motor symptoms, HD is marked by cognitive impairment and behavioral changes. In this study, we analyzed the blood of HD gene carries using RNA-sequencing techniques. We evaluated samples from HD gene carriers with (

Indexed as

AdultCase-Control StudiesComorbidityDepressionDisease ProgressionDown-RegulationFemaleGene Expression ProfilingHumansHuntington DiseaseMaleMiddle AgedNeurodegenerative DiseasesTranscriptomeUp-RegulationdepressionHuntington’s diseaseneurodegenerative diseaseneurodevelopmentRNA-seq

Identifiers

PMID33187165
PMCPMC7697115
OpenAlexW3099048258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.