Evidence map›Paper›PMID 33187125›Full record

ArticleInternational journal of environmental research and public health2020

Nonparametric Limits of Agreement in Method Comparison Studies: A Simulation Study on Extreme Quantile Estimation.

Oke Gerke

Abstract readComparative Study
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
  2. Comparison ofMicrobiology spectrum · 2026
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  3. Application of the patient-reported and nurse-rated Richards-Campbell Sleep Questionnaire in neurorehabilitation inpatients.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

1 author.

Oke GerkeDepartment of Nuclear Medicine, Odense University Hospital, 5000 Odense C, Denmark.ORCID 0000-0001-6335-3303

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bland-Altman limits of agreement and the underlying plot are a well-established means in method comparison studies on quantitative outcomes. Normally distributed paired differences, a constant bias, and variance homogeneity across the measurement range are implicit assumptions to this end. Whenever these assumptions are not fully met and cannot be remedied by an appropriate transformation of the data or the application of a regression approach, the 2.5% and 97.5% quantiles of the differences have to be estimated nonparametrically. Earlier, a simple Sample Quantile (SQ) estimator (a weighted average of the observations closest to the target quantile), the Harrell-Davis estimator (HD), and estimators of the Sfakianakis-Verginis type (SV) outperformed 10 other quantile estimators in terms of mean coverage for the next observation in a simulation study, based on sample sizes between 30 and 150. Here, we investigate the variability of the coverage probability of these three and another three promising nonparametric quantile estimators with n=50(50)200,250(250)1000. The SQ estimator outperformed the HD and SV estimators for n=50 and was slightly better for n=100, whereas the SQ, HD, and SV estimators performed identically well for n≥150. The similarity of the boxplots for the SQ estimator across both distributions and sample sizes was striking.

Indexed as

Computer SimulationResearch DesignStatistics, NonparametricBiasProbabilityagreementBland–Altman analysiscoveragelimits of agreementmethod comparisonquantile estimationrepeatabilityreproducibility

Identifiers

PMID33187125
PMCPMC7698333

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.