Evidence map›Paper›PMID 33186891›Full record

ReviewCurrent opinion in cell biology2021

Roles for microtubules in the proliferative and differentiated cells of stratified epithelia.

Daniel Hlavaty, Terry Lechler

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Desmosomes at a glance.Journal of cell science · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel HlavatyDepartments of Dermatology and Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.
Terry LechlerDepartments of Dermatology and Cell Biology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: terry.lechler@duke.edu.
Duke University · US

Funding

Spindle Orientation in Skin Development and HomeostasisR01AR067203 · NIAMS · DUKE UNIVERSITY · PI LECHLER, TERRY H · 2015 to 2025
$3.9M
Role of Cell Adhesion and the Cytoskeleton in Epidermal IntegrityR01AR055926 · NIAMS · DUKE UNIVERSITY · PI LECHLER, TERRY H · 2009 to 2019
$3.7M
NIAMS NIH HHS R01 AR055926NIAMS NIH HHS R01 AR067203
6 · The paper itself

Abstract

While microtubule dynamics and organization have been extensively studied invitro, both biochemically and in cultured cells, recent work has begun to extend this into tissues ex vivo and organisms in vivo. Advances in genetic tools and imaging technology have allowed studies on the dynamics, function, and organization of microtubules in the stratified epithelia of the epidermis. Here, we discuss recent work that highlights the varied roles that microtubules play in supporting epidermal function. These findings demonstrate that studying microtubules in tissues has revealed not only novel aspects of epidermal biology but also new principles of microtubule regulation.

Indexed as

AnimalsCell DifferentiationCentrosomeCiliaEpidermal CellsHumansKeratinocytesMicrotubulesSignal TransductionSkinCentrosomeCiliaDesmosomesDifferentiationEpidermisGammatubulinMicrotubuleSkin

Identifiers

PMID33186891
PMCPMC7925363
OpenAlexW3104775356

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.