Evidence map›Paper›PMID 33186869›Full record

ReviewCurrent opinion in immunology2020

Vaping and e-cigarette use. Mysterious lung manifestations and an epidemic.

Alicia M Casey, Eleanor D Muise, Laura E Crotty Alexander

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Zebrafish (International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. THC and CBD: Villain versus Hero? Insights into Adolescent Exposure.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Article
  17. Electronic Cigarettes and Asthma: What Do We Know So Far?Journal of personalized medicine · 2021
    Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alicia M CaseyDivision of Pulmonary Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, United States.
Eleanor D MuiseDivision of Pulmonary Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02215, United States.
Laura E Crotty AlexanderPulmonary Critical Care Section, VA San Diego Healthcare System, La Jolla, CA 92161, United States; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego (UCSD), La Jolla, CA 92093, United States. Electronic address: LCA@ucsd.edu.
Boston Children's Hospital · USUC San Diego Health System · US

Funding

Electronic Cigarette Vapor Inhalation Adversely Affects Lung Cellular and Physiologic Function and Alters Systemic Inflammatory PathwaysR01HL137052 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CROTTY ALEXANDER, LAURA ELISE · 2017 to 2021
$2.3M
Prospective Health Outcomes and Inflammatory Biomarkers Associated with e-Cigarette UseR01HL147326 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CASTALDI, PETER · 2019 to 2021
$1.5M
Joint Initiative in Vaccine Economics 5U01IP000965 · IP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUTTON, DAVID W · 2015 to 2017
$899k
Rochester Center for Adolescent Immunization ResearchU01IP000040 · IP · UNIVERSITY OF ROCHESTER · PI SZILAGYI, PETER G · 2004 to 2006
$273k
Hypoxia inducible factors in pulmonary endothelial cells regulate allergic inflammatory airways diseaseI01BX004767 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CROTTY ALEXANDER, LAURA ELISE · 2020 to 2023
–
ACL HHS U01IP000965BLRD VA I01 BX004767NCIRD CDC HHS U01 IP000040NCIRD CDC HHS U01 IP000965NHLBI NIH HHS R01 HL137052NHLBI NIH HHS R01 HL147326
6 · The paper itself

Abstract

Electronic (e)-cigarette use and the practice of vaping has rapidly expanded both in adult smokers and previously nicotine naïve youths. Research has focused on harm reduction in adults using e-cigarettes to stop or reduce traditional cigarette use, but the short and long-term safety of these products has not been established. Vaping has more recently been associated with a growing list of pulmonary complications with the most urgent being the e-cigarette or vaping product use-associated lung injury (EVALI) epidemic. This review details the inhalant toxicology of vaping products, the described lung diseases associated with vaping with a focus on EVALI, and the predicted long-term consequences of e-cigarette use, including increased asthma severity.

Indexed as

Electronic Nicotine Delivery SystemsVapingHumansLung Injury

Identifiers

PMID33186869
PMCPMC7755270
OpenAlexW3104146675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.