Evidence map›Paper›PMID 33186723›Full record

ArticleNeuroImage2021

NOise reduction with DIstribution Corrected (NORDIC) PCA in dMRI with complex-valued parameter-free locally low-rank processing.

Steen Moeller, Pramod Kumar Pisharady, Sudhir Ramanna, Christophe Lenglet, Xiaoping Wu, Logan Dowdle, Essa Yacoub, Kamil Uğurbil, Mehmet Akçakaya

Abstract read
In one paragraph

Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Neural Tuning for Ordinal Processing: Convergent Patterns in Human Brains and Artificial Networks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Steen MoellerCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA. Electronic address: moeller@cmrr.umn.edu.
Pramod Kumar PisharadyCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Sudhir RamannaCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Christophe LengletCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Xiaoping WuCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Logan DowdleCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Essa YacoubCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Kamil UğurbilCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA.
Mehmet AkçakayaCenter for Magnetic Resonance Research (CMRR), Department of Radiology, University of Minnesota, Minneapolis, MN, USA; Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, USA.

Funding

TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger · 2019 to 2026
$11.7M
Elementary Neuronal Ensembles to Whole Brain Networks: Ultrahigh Resolution Imaging of Function and Connectivity in Humans - SUPPLEMENTU01EB025144 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2017 to 2022
$9.7M
NIBIB NIH HHS P41 EB027061NIBIB NIH HHS U01 EB025144
6 · The paper itself

Abstract

Diffusion-weighted magnetic resonance imaging (dMRI) has found great utility for a wide range of neuroscientific and clinical applications. However, high-resolution dMRI, which is required for improved delineation of fine brain structures and connectomics, is hampered by its low signal-to-noise ratio (SNR). Since dMRI relies on the acquisition of multiple different diffusion weighted images of the same anatomy, it is well-suited for denoising methods that utilize correlations across the image series to improve the apparent SNR and the subsequent data analysis. In this work, we introduce and quantitatively evaluate a comprehensive framework, NOise Reduction with DIstribution Corrected (NORDIC) PCA method for processing dMRI. NORDIC uses low-rank modeling of g-factor-corrected complex dMRI reconstruction and non-asymptotic random matrix distributions to remove signal components which cannot be distinguished from thermal noise. The utility of the proposed framework for denoising dMRI is demonstrated on both simulations and experimental data obtained at 3 Tesla with different resolutions using human connectome project style acquisitions. The proposed framework leads to substantially enhanced quantitative performance for estimating diffusion tractography related measures and for resolving crossing fibers as compared to a conventional/state-of-the-art dMRI denoising method.

Indexed as

ArtifactsAlgorithmsBrainConnectomeDiffusion Magnetic Resonance ImagingHumansImage Processing, Computer-AssistedSignal-To-Noise RatioBrain imagingDenoisingDiffusion MRIHuman connectome projectMultibandSimultaneous multi-sliceSingular value decomposition

Identifiers

PMID33186723
PMCPMC7881933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.