ReviewAmerican journal of infection control2021
Use of powered air-purifying respirator(PAPR) as part of protective equipment against SARS-CoV-2-a narrative review and critical appraisal of evidence.
Review in American journal of infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- A systematic review of fit improvement strategies for respirators: lessons learned from the COVID-19 pandemic.BMC public health · 2025Pooled it
- A Review of Filtration Performance of Protective Masks.International journal of environmental research and public health · 2023Pooled it
- Reframing Pandemic Preparedness: Why Positive-Pressure Exposure Control Merits Formal Public Health Evaluation.JMIR public health and surveillance · 2026Article
- Self-contamination risk and failure modes during high-level PPE doffing: A pilot comparison of 2 powered air-purifying respirator (PAPR) hoods.American journal of infection control · 2025Article
- Powered Air Purifying Respirators (PAPRs) for Protection from Respirable Dust in Underground Mines.Mining, metallurgy & exploration · 2025Review
- Swallowing during provision of helmet ventilation: Review and provisional multidisciplinary guidance.Journal of the Intensive Care Society · 2024Article
- Factors influencing nurses' compliance related to the use of personal protective equipment during the COVID-19 pandemic: A descriptive cross-sectional study.Nursing open · 2024Article
- A manikin-based assessment of loose-fitting powered air-purifying respirator performance at variable flow rates and work rates.Journal of occupational and environmental hygiene · 2023Article
- Scaling Biosafety Up During and Down After the COVID-19 Pandemic.Applied biosafety : journal of the American Biological Safety Association · 2022Review
- Exploring healthcare workers' perspectives of video feedback for training in the use of powered air purifying respirators (PAPR) at the onset of the COVID-19 pandemic.BMC medical education · 2022Article
- New Zealand Emergency Department COVID-19 Preparedness: a cross-sectional survey and narrative view.BMJ open · 2022Article
- Risk of Dehydration Due to Sweating While Wearing Personal 2 Protective Equipment in COVID-19 Clinical Care: A Pilot Study.Healthcare (Basel, Switzerland) · 2022Article
- Article
- Physiotherapy management for COVID-19 in the acute hospital setting and beyond: an update to clinical practice recommendations.Journal of physiotherapy · 2022Article
- Impact of Personal Protective Equipment on Out-of-Hospital Cardiac Arrest Resuscitation in Coronavirus Pandemic.Medicina (Kaunas, Lithuania) · 2021Article
- Revised recommendations from the CSO-HNS taskforce on performance of tracheotomy during the COVID-19 pandemic - what a difference a year makes.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2021Article
- N95 respirator and surgical mask effectiveness against respiratory viral illnesses in the healthcare setting: A systematic review and meta-analysis.Journal of the American College of Emergency Physicians open · 2021Article
- Review
- Fit-testing of respiratory protective equipment in the UK during the initial response to the COVID-19 pandemic.The Journal of hospital infection · 2021Article
- Development of an emergency airway response system for COVID-19 at a tertiary care hospital in resource limited country.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe last 2 decades have seen an increasing frequency of zoonotic origin viral diseases leaping from animal to human hosts including Severe Acute Respiratory Syndrome Coronaviruses (SARS-CoV-2). Respiratory component of the infectious disease program against SARS-CoV-2 incorporates use of protective airborne respiratory equipment.
methodsIn this narrative review, we explore the features of Powered Air Purifying Respirators (PAPR) as well as logistical and evidence-based advantages and disadvantages.
resultsSimulation study findings support increased heat tolerance and wearer comfort with a PAPR, versus decreased communication ability, mobility, and dexterity. Although PAPRs have been recommended for high-risk procedures on suspected or confirmed COVID-19 patients, this recommendation remains controversial due to lack of evidence. Guidelines for appropriate use of PAPR during the current pandemic are sparse. International regulatory bodies do not mandate the use of PAPR for high-risk aerosol generating procedures in patients with SARS-CoV-2. Current reports of the choice of protective respiratory technology during the SARS-CoV-2 pandemic are disparate. Patterns of use appear to be related to geographical locations. DISCUSSION: Field observational studies do not indicate a difference in healthcare worker infection utilizing PAPR devices versus other compliant respiratory equipment in healthcare workers performing AGPs in patients with SARS-CoV-2. Whether a higher PAPR filtration factor translates to decreased infection rates of HCWs remains to be elucidated. Utilization of PAPR with high filtration efficiency may represent an example of "precautionary principle" wherein action taken to reduce risk is guided by logistical advantages of PAPR system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.