ArticleCurrent biology : CB2021
Astroglial Calcium Signaling Encodes Sleep Need in Drosophila.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 111 citations in OpenAlex.
- A molecular integrator of sleep duration and interruption.bioRxiv : the preprint server for biology · 2026Article
- Review
- Links Between Autophagy and Healthy Aging.Journal of molecular biology · 2026Review
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- Regulation of Metabolic Rhythms by Glial Clocks.Journal of biological rhythms · 2026Article
- The use ofFrontiers in cell and developmental biology · 2026Review
- Contributions of Zebrafish to Our Understanding of the Function and Regulation of Sleep.Current sleep medicine reports · 2026Review
- Sleep regulation inFrontiers in neuroscience · 2026Review
- Sleep rescues age-associated loss of glial engulfment.PLoS genetics · 2026Article
- Lifestyle Drives Astroglial Plasticity Toward Cognitive Improvement: Roles of Physical Exercise, Environmental Enrichment, Diet, and Sleep.Molecular neurobiology · 2025Review
- Dysregulation of Glial Gap Junction Protein Innexin2 Mediates Seizures and Disrupted Sleep in a Drosophila Model for North Sea Progressive Myoclonus Epilepsy.Journal of neuroscience research · 2025Article
- A basic role for glia in sleep homeostasis.Nature neuroscience · 2025Article
- Dynamics of glia and neurons regulate homeostatic rest, sleep and feeding behavior in Drosophila.Nature neuroscience · 2025Article
- Astrocytes at the heart of sleep: from genes to network dynamics.Cellular and molecular life sciences : CMLS · 2025Review
- GPCR signaling gates astrocyte responsiveness to neurotransmitters and control of neuronal activity.Science (New York, N.Y.) · 2025Article
- The Duality of Astrocyte Neuromodulation: Astrocytes Sense Neuromodulators and Are Neuromodulators.Journal of neurochemistry · 2025Review
- FlyVISTA, an integrated machine learning platform for deep phenotyping of sleep inScience advances · 2025Article
- Review
- Astrocyte regulation of behavioral outputs: the versatile roles of calcium.Frontiers in cellular neuroscience · 2025Review
- Glial Regulation of Circuit Wiring, Firing, and Expiring in theCold Spring Harbor perspectives in biology · 2024Review
11 more citing papers are in PubMed but not listed here.
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
Abstract
Sleep is under homeostatic control, whereby increasing wakefulness generates sleep need and triggers sleep drive. However, the molecular and cellular pathways by which sleep need is encoded are poorly understood. In addition, the mechanisms underlying both how and when sleep need is transformed to sleep drive are unknown. Here, using ex vivo and in vivo imaging, we show in Drosophila that astroglial Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.