Evidence map›Paper›PMID 33186212›Full record

ReviewJournal of the Chinese Medical Association : JCMA2021

Highlight of severe acute respiratory syndrome coronavirus-2 vaccine development against COVID-19 pandemic.

Cheng-Hsuan Liu, Hsuan-Yang Huang, Yung-Fang Tu, Wei-Yi Lai, Chia-Lin Wang, Jun-Ren Sun, Yueh Chien, Tzu-Wei Lin, Yi-Ying Lin, Chian-Shiu Chien and 5 more

Abstract readReview
In one paragraph

Review in Journal of the Chinese Medical Association : JCMA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Cheng-Hsuan LiuDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Hsuan-Yang HuangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yung-Fang TuDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Wei-Yi LaiDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chia-Lin WangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Jun-Ren SunInstitute of Preventive Medicine, National Defense Medical Center, Taipei, Taiwan, ROC.
Yueh ChienDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Tzu-Wei LinDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Yi-Ying LinDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chian-Shiu ChienDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Chih-Heng HuangInstitute of Preventive Medicine, National Defense Medical Center, Taipei, Taiwan, ROC.
Yuh-Min ChenSchool of Medicine, National Yang-Ming Medical University, Taipei, Taiwan, ROC.
Pin-I HuangSchool of Medicine, National Yang-Ming Medical University, Taipei, Taiwan, ROC.
Fu-Der WangSchool of Medicine, National Yang-Ming Medical University, Taipei, Taiwan, ROC.
Yi-Ping YangDepartment of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has brought an unprecedented impact upon the global economy and public health. Although the SARS-CoV-2 virology has been gradually investigated, measures to combat this new threat in public health are still absent. To date, no certificated drug or vaccine has been developed for the treatment or prevention of coronavirus disease Extensive researches and international coordination has been conducted to rapidly develop novel vaccines against SARS-CoV-2 pandemic. Several major breakthroughs have been made through the identification of the genetic sequence and structural/non-structural proteins of SARS-CoV-2, which enabled the development of RNA-, DNA-based vaccines, subunit vaccines, and attenuated viral vaccines. In this review article, we present an overview of the recent advances of SARS-CoV-2 vaccines and the challenges that may be encountered in the development process, highlighting the advantages and disadvantages of these approaches that may help in effectively countering COVID-19.

Indexed as

COVID-19COVID-19 VaccinesHumansmRNA VaccinesSARS-CoV-2Vaccines, DNAVaccines, SubunitVaccines, SyntheticCOVID-19 VaccinesmRNA VaccinesVaccines, DNAVaccines, SubunitVaccines, Synthetic

Identifiers

PMID33186212
PMCPMC12966110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.