ArticleThe American journal of drug and alcohol abuse2020
Adverse childhood experiences are associated with at-risk drinking, cannabis and illicit drug use in females but not males: an Emergency Department study.
Article in The American journal of drug and alcohol abuse, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The trial behind it
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Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Gender Differences in the Association Between Adverse Childhood Experiences and Health Risk Behaviors in the Mountain West.AJPM focus · 2026Article
- Predicting Substance Use in Young Adults: The Role of Childhood Adversity.Medicina (Kaunas, Lithuania) · 2026Article
- Early Adverse Experiences and the Likelihood of Substance Use Disorders and Non-Fatal Overdose in Clinical and Community Settings: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2026Review
- Drug misuse, self-esteem, and intimate partner violence among low-income African American women.Psychological trauma : theory, research, practice and policy · 2025Article
- Risk Factors and Onset of Illicit Drug Use among Filipino Youth: A Cross-sectional Analysis of Sociodemographic and Environmental Influences.Acta medica Philippina · 2025Article
- Positive Childhood Experiences are Associated With Alcohol Use in Adolescent and Emerging Adult Females by Adverse Childhood Experiences Dimension.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2024Article
- Two-part models identifying predictors of cigarette, e-cigarette, and cannabis use and change in use over time among young adults in the US.The American journal on addictions · 2024Article
- Trauma-informed Care Training in Trauma and Emergency Medicine: A Review of the Existing Curricula.The western journal of emergency medicine · 2024Review
- Neuroendocrine mechanisms in the links between early life stress, affect, and youth substance use: A conceptual model for the study of sex and gender differences.Frontiers in neuroendocrinology · 2024Review
- Adverse Childhood Experiences and Associations with Mental Health, Substance Use, and Violence Perpetration among Young Adults in sub-Saharan Africa.Child abuse & neglect · 2024Article
- Patterns of Adverse Childhood Experiences and Problematic Health Outcomes Among US Young Adults: A Latent Class Analysis.Substance use & addiction journal · 2024Article
- Sex Differences in the Relationship Between Nucleus Accumbens Volume and Youth Tobacco or Marijuana Use Following Stressful Life Events.Journal of mental health & clinical psychology · 2024Article
- Differential prevalence of Adverse Childhood Experiences (ACEs) by gender and substance used in individuals with cannabis, cocaine, opioid, and tobacco use disorders.The American journal of drug and alcohol abuse · 2023Article
- Regular cannabis use is associated with history of childhood and lifetime trauma in a non-clinical community sample.Journal of psychiatric research · 2023Article
- The Association Between Adverse and Positive Childhood Experiences and Marijuana Use During Lactation.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2023Article
- Mental health adverse events with cannabis use diagnosed in the Emergency Department: what are we finding now and are our findings accurate?Frontiers in psychiatry · 2023Review
- Expanded Adverse Childhood Experiences (ACEs) and Adult Cannabis Use: A Latent Class Analysis.Cannabis (Albuquerque, N.M.) · 2023Article
- Absent mindfulness: mediation analyses of the relationship between adverse childhood experiences and disordered eating among young adults.Frontiers in child and adolescent psychiatry · 2023Article
- Association of Cannabis Use and At-Risk Alcohol Use With Intimate Partner Violence in an Urban ED Sample.Journal of emergency nursing · 2022Article
- Psychosocial predictors of longitudinal changes in tobacco and cannabis use among young adults.Addictive behaviors · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAdverse childhood experiences (ACEs) are associated with adult substance use in the general population. Given pervasive health disparities among underserved populations, understanding how ACEs are associated with substance use among urban Emergency Department (ED) patients could help inform design of effective screening, brief interventions, and referral to treatment.
objectivesTo estimate gender differences in prevalence of separate and cumulative ACEs among a sample of urban ED patients, and assess its association with at-risk drinking (4+/5+ drinks for females/males), cannabis, and illicit drug use. We hypothesized that the association between ACEs and each outcome would be stronger among females than males.
methodsCross-sectional survey data were obtained from 1,037 married/partnered ED patients (53% female) at a public safety-net hospital. Gender-stratified logistic regression models were estimated for each substance use outcome.
resultsOne+ ACEs were reported by 53% of males and 60% of females. Females whose mother was a victim of domestic violence had greater odds of at-risk drinking compared to females who did not report this ACE (AOR = 1.72; 95% CI 1.03, 2.88). Females' cumulative ACEs were associated with cannabis use (OR = 2.26, 95% CI 1.06, 4.83) and illicit drug use (OR = 3.35; 95% CI 1.21, 9.30). Males' separate and cumulative ACEs were not associated with increased likelihood for any of the outcomes.
conclusionACEs are associated with greater odds of substance use among female than male ED patients. The prevalence of ACE exposure in this urban ED sample underscores the importance of ED staff providing trauma-informed care.
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Registered trials
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