Evidence map›Paper›PMID 33185967›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Rapid and Selective Chemical Editing of Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) via Cu

Reinder H de Vries, Jakob H Viel, Oscar P Kuipers, Gerard Roelfes

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Peptide Boronic Acids by Late-Stage Hydroboration on the Solid Phase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  6. Review
  7. Desulfurative Borylation of Small Molecules, Peptides, and Proteins.Journal of the American Chemical Society · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Umpolung AlaAngewandte Chemie (International ed. in English) · 2022
    Article
  13. 1,4,6,10-Tetraazaadamantanes (TAADs) withBeilstein journal of organic chemistry · 2022
    Article
  14. Merging the Versatile Functionalities of Boronic Acid with Peptides.International journal of molecular sciences · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Reinder H de VriesStratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747, AG, Groningen, The Netherlands.
Jakob H VielDepartment of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747, AG, Groningen, The Netherlands.
Oscar P KuipersDepartment of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747, AG, Groningen, The Netherlands.ORCID 0000-0001-5596-7735
Gerard RoelfesStratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747, AG, Groningen, The Netherlands.ORCID 0000-0002-0364-9564

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the fast and selective chemical editing of ribosomally synthesized and post-translationally modified peptides (RiPPs) by β-borylation of dehydroalanine (Dha) residues. The thiopeptide thiostrepton was modified efficiently using Cu

Indexed as

AlanineAnti-Bacterial AgentsBoronic AcidsCatalysisCopperEnterococcus faecalisMicrobial Sensitivity TestsNisinProtein Processing, Post-TranslationalRibosomesSolubilityStaphylococcus aureusThiazolesThiostreptonAlanineAnti-Bacterial AgentsBoronic AcidsCopperdehydroalanineNisinnisin ZnosiheptideThiazolesThiostreptondehydroalaninelate-stage chemical editingpeptide modificationRiPPsβ-borylation

Identifiers

PMID33185967
PMCPMC7898795

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.