Evidence map›Paper›PMID 33185800›Full record

ReviewMagma (New York, N.Y.)2021

Hyperpolarization via dissolution dynamic nuclear polarization: new technological and methodological advances.

Arthur C Pinon, Andrea Capozzi, Jan Henrik Ardenkjær-Larsen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Magma (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Effective Hamiltonian-Based DNP Sequence Optimization.The journal of physical chemistry letters · 2026
    Article
  3. Review
  4. Live Metabolomics with NMR.Analytical chemistry · 2026
    Review
  5. The journal of physical chemistry. B · 2025
    Article
  6. SABRE Ir-IMes Catalysis for the Masses.Molecules (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. The solid effect of dynamic nuclear polarization in liquids.Magnetic resonance (Gottingen, Germany) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Arthur C PinonDepartment of Health Technology, Center for Hyperpolarization in Magnetic Resonance, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark.
Andrea CapozziDepartment of Health Technology, Center for Hyperpolarization in Magnetic Resonance, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark.
Jan Henrik Ardenkjær-LarsenDepartment of Health Technology, Center for Hyperpolarization in Magnetic Resonance, Technical University of Denmark, Building 349, 2800, Kgs Lyngby, Denmark. jhar@dtu.dk.ORCID http://orcid.org/0000-0001-6167-6926

Funding

Danmarks Grundforskningsfond DNRF124H2020 Marie Skłodowska-Curie Actions 713683H2020 Marie Skłodowska-Curie Actions 858149
6 · The paper itself

Abstract

Dissolution-DNP is a method to boost liquid-state NMR sensitivity by several orders of magnitude. The technique consists in hyperpolarizing samples by solid-state dynamic nuclear polarization at low temperature and moderate magnetic field, followed by an instantaneous melting and dilution of the sample happening inside the polarizer. Although the technique is well established and the outstanding signal enhancement paved the way towards many applications precluded to conventional NMR, the race to develop new methods allowing higher throughput, faster and higher polarization, and longer exploitation of the signal is still vivid. In this work, we review the most recent advances on dissolution-DNP methods trying to overcome the original technique's shortcomings. The review describes some of the new approaches in the field, first, in terms of sample formulation and properties, and second, in terms of instrumentation.

Indexed as

Magnetic Resonance ImagingCold TemperatureMagnetic FieldsMagnetic Resonance SpectroscopySolubilityBullet-DNPCross-polarizationCryogen-freedDNPDynamic nuclear polarizationHyperpolarizationNon-persistent radicals

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.