ReviewSurgery today2021
Clinical outcomes of patients after nipple-sparing mastectomy and reconstruction based on the expander/implant technique.
Review in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Targeted Nipple-Areola Complex (NAC) Reinnervation (TNR): A Systematic Review and Meta-Analysis.Aesthetic plastic surgery · 2026Pooled it
- Nipple or skin-sparing mastectomy flap: can preoperative breast-MRI predict post-operative complications?Updates in surgery · 2026Article
- Early Experience with Synthetic Monofilament Polydioxanone Mesh in Primary Breast Reconstruction: A Propensity Matched Analysis.Archives of plastic surgery · 2026Article
- Single-Port Robot-Assisted Nipple-Sparing Mastectomy: Main Analysis of a Retrospective Multicenter Study (SPROUT, KoREa-BSG 09).Annals of surgical oncology · 2026Article
- Shifting Practice Patterns in Implant-based Breast Reconstruction in China: Insights From a 13-year Large-scale Retrospective Cohort.Plastic and reconstructive surgery. Global open · 2026Article
- Minimally Invasive Nipple-Sparing Mastectomy: Early Experience With Endoscopic and Robotic Techniques.European journal of breast health · 2026Article
- Predictors of Complications in Prophylactic Mastectomy and Direct-to-Implant Breast Reconstruction: A Retrospective, Single-Center Study.Journal of clinical medicine · 2026Article
- "Safety and efficacy of early drain removal in breast reconstruction: a retrospective cohort study".Breast cancer (Tokyo, Japan) · 2026Article
- Does Breast Implant Size Larger Than Mastectomy Specimen Size Increase the Risk of Flap Necrosis?Aesthetic surgery journal. Open forum · 2026Article
- Is a soft tissue reinforcing mesh necessary in immediate prosthetic breast reconstruction for early breast cancer in patients with low-volume breast? A single-center, retrospective Chinese clinical study.Updates in surgery · 2023Article
- Mastectomy with one-stage or two-stage reconstruction in breast cancer: analysis of early outcomes and patient's satisfaction.Updates in surgery · 2023Article
- Short- and long-term outcomes of immediate breast reconstruction surgery after neoadjuvant chemotherapy.Surgery today · 2022Article
- Role of Qualitative and Quantitative Indocyanine Green Angiography to Assess Mastectomy Skin Flaps Perfusion in Nipple/Skin-Sparing and Skin-Reducing Mastectomies with Implant-Based Breast Reconstruction.The breast journal · 2022Article
- Breakthrough in breast reconstruction in the context of COVID-19: safety and efficiency of endoscopic breast reconstruction at a day surgery center.Gland surgery · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advances in multi-modality treatments incorporating systemic chemotherapy, endocrine therapy, and radiotherapy for the management of breast cancer have resulted in a surgical-management paradigm change toward less-aggressive surgery that combines the use of breast-conserving or -reconstruction therapy as a new standard of care with a higher emphasis on cosmesis. The implementation of skin-sparing and nipple-sparing mastectomies (SSM, NSM) has been shown to be oncologically safe, and breast reconstructive surgery is being performed increasingly for patients with breast cancer. NSM and breast reconstruction can also be performed as prophylactic or risk-reduction surgery for women with BRCA gene mutations. Compared with conventional breast construction followed by total mastectomy (TM), NSM preserving the nipple-areolar complex (NAC) with breast reconstruction provides psychosocial and aesthetic benefits, thereby improving patients' cosmetic appearance and body image. Implant-based breast reconstruction (IBBR) has been used worldwide following mastectomy as a safe and cost-effective method of breast reconstruction. We review the clinical evidence about immediate (one-stage) and delayed (two-stage) IBBR after NSM. Our results suggest that the postoperative complication rate may be higher after NSM followed by IBBR than after TM or SSM followed by IBBR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.