SynthesisInternational urology and nephrology2021
Vacuum-assisted closure device in the postoperative wound care for Fournier's gangrene: a systematic review.
Synthesis in International urology and nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 21 citations in OpenAlex.
- Outcomes of vacuum-assisted closure therapy (VAC) in patients with Fournier's gangrene: a retrospective cohort study.Irish journal of medical science · 2026Article
- Cellulose-Based Nanofibers Infused with Biotherapeutics for Enhanced Wound-Healing Applications.ACS polymers Au · 2025Review
- The Subacute Necrotizing Fasciitis: The Forgotten form of this Life-threatening Infection. A Case Report.Journal of orthopaedic case reports · 2023Article
- Bibliometric insights in fournier's gangrene: Research landscapes, turning points, and global trends.Frontiers in surgery · 2023Review
- Contralateral necrotizing fascitis after left nephrectomy for emphysematous pyelonephritis.IJU case reports · 2022Article
- Fournier's gangrene with prostatic and bladder trigone colliquation: a suggested treatment algorithm.BMJ case reports · 2022Article
- Management of Fournier's gangrene during the Covid-19 pandemic era: make a virtue out of necessity.Basic and clinical andrology · 2022Article
- Progress in Multidisciplinary Treatment of Fournier's Gangrene.Infection and drug resistance · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the effectiveness of Vacuum-Assisted Closure Device in the postoperative wound care for Fournier's gangrene
methodsWe performed a systematic review in the following databases: Medline (Ovid), EMBASE, and The Cochrane Central Register of Controlled Trials (CENTRAL), from inception to nowadays. We included RCTs and analytical observational studies. Meta-analysis was not possible given the clinical and methodological heterogeneity of the studies.
resultsWe included six studies that compared VAC treated patients and a control group. The length of stay of the VAC treated vs. the conventional dressing treated patients was higher for the VAC treated patients in all but one of the included studies. The VAC group had the highest number of surgical debridements requiring anesthesia. The conventionally treated patients had a higher number of daily dressings, and the need for additional dressing changes, without anesthesia. Two studies found significantly higher mean scores for VAS, requiring a higher need for daily analgesics for the control group patients.
conclusionsVAC therapy is an effective method, but it is not better than conventional dressing treatment. VAC carries fewer dressing changes, less pain, and less need for analgesics, but it comes with a higher need for surgical interventions requiring anesthesia.
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Registered trials
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