ArticleEuropean radiology2021
Feasibility and reproducibility of T2 mapping and DWI for identifying malignant lymph nodes in rectal cancer.
Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- PET/MRI is superior to PET/CT in detecting oesophago and gastric carcinomas: a meta-analysis.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Pooled it
- Apparent diffusion coefficient cannot discriminate metastatic and non-metastatic lymph nodes in rectal cancer: a meta-analysis.International journal of colorectal disease · 2021Pooled it
- Quantitative T2 mapping of junctional zone alterations in endometrial fibrosis: comparison with diffusion-weighted imaging.Quantitative imaging in medicine and surgery · 2026Article
- Preoperative synthetic magnetic resonance imaging-based biomarkers for predicting tumor budding of rectal cancer.BMC medical imaging · 2026Article
- An Interpretable Machine Learning Model With Synthetic MRI-Based Habitat Radiomics for Predicting Lymph Node Metastasis in Oral Cancer.Cancer medicine · 2026Article
- Abdominal simultaneous 3D water TMagnetic resonance in medicine · 2026Article
- Enhancing the role of MRI in rectal cancer: advances from staging to prognosis prediction.European radiology · 2025Review
- Assessment of magnetic resonance image compilation (MAGiC) abilities of therapeutic selection and prediction on recurrence risk factors and short-term treatment efficacy in cervical cancer.La Radiologia medica · 2025Article
- Preoperative prediction of lymph node metastasis in pancreatic ductal adenocarcinoma using MRI-derived whole-tumor ADC histogram analysis.Frontiers in medicine · 2025Article
- Application of cellular microstructural diffusion MRI (cell size imaging) in rectal lesions: a preliminary study.Frontiers in oncology · 2025Article
- Development and validation of machine learning-based MRI radiomics models for preoperative lymph node staging in T3 rectal cancer.Frontiers in oncology · 2025Article
- Synthetic MRI and diffusion-weighted imaging for differentiating nasopharyngeal lymphoma from nasopharyngeal carcinoma: combination with morphological features.The British journal of radiology · 2024Article
- Reproducibility and repeatability of quantitative T2 and T2* mapping of osteosarcomas in a mouse model.European radiology experimental · 2024Article
- Evaluating the added value of synthetic magnetic resonance imaging in predicting sentinel lymph node status in breast cancer.Quantitative imaging in medicine and surgery · 2024Article
- The value of multiparameter MRI of early cervical cancer combined with SCC-Ag in predicting its pelvic lymph node metastasis.Frontiers in oncology · 2024Article
- T1 mapping in evaluation of clinicopathologic factors for rectal adenocarcinoma.Abdominal radiology (New York) · 2024Article
- Predicting the status of lymphovascular space invasion using quantitative parameters from synthetic MRI in cervical squamous cell carcinoma without lymphatic metastasis.Frontiers in oncology · 2024Article
- T1 and T2 mapping for identifying malignant lymph nodes in head and neck squamous cell carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Quantitative evaluation of diffusion-weighted MRI for differentiating benign and malignant thyroid nodules larger than 4 cm.BMC medical imaging · 2023Article
- Radiomic Analysis of Quantitative T2 Mapping and Conventional MRI in Predicting Histologic Grade of Bladder Cancer.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate the diagnostic value and reproducibility of T2 mapping versus apparent diffusion coefficients (ADC) for identifying malignant lymph nodes in patients with non-mucinous rectal adenocarcinoma.
methodsHigh-resolution magnetic resonance imaging, diffusion-weighted imaging, and T2 mapping were performed on patients with suspected metastatic lymph nodes in the mesorectum or around the superior rectal artery with a short-axis diameter of 4-10 mm. The T2 and ADC values of pathology-confirmed metastatic versus non-metastatic lymph nodes were compared using the independent-samples t test and receiver operating characteristic curves. Intra- and inter-observer reproducibility were tested. The cutoff value for T2 relaxation time was determined.
resultsIn total, 67 lymph nodes underwent histological analysis, with 24 in the non-metastatic and 43 in the metastatic groups. Intra- and inter-observer agreements for T2 values were 0.999 and 0.998, respectively, which were higher than the ADC values of 0.924 and 0.844, respectively. The mean T2 and ADC values for metastatic lymph nodes (65 ± 7.8 ms and 1.17 ± 0.16 × 10
conclusionsT2 mapping had higher diagnostic efficacy and reproducibility than ADC and may be useful in differentiating metastatic from non-metastatic lymph nodes in rectal cancer. KEY POINTS: • Mean T2 values were significantly shorter for malignant versus benign LNs in patients with non-mucinous rectal adenocarcinoma. • The diagnostic efficacy and reproducibility of T2 values were excellent and superior to ADC values.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.