Evidence map›Paper›PMID 33185706›Full record

ArticleInternational journal of legal medicine2021

Age estimation based on 3D pulp chamber segmentation of first molars from cone-beam-computed tomography by integrated deep learning and level set.

Qiang Zheng, Zhipu Ge, Han Du, Gang Li

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of legal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Age Estimation Using Maxillary Central Incisor Analysis on Cone Beam Computed Tomography Human Images.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Qiang ZhengSchool of Computer and Control Engineering, Yantai University, Yantai, China.
Zhipu GeDepartment of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology, Beijing, China.
Han DuDepartment of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology, Beijing, China.
Gang LiDepartment of Oral and Maxillofacial Radiology, Peking University School and Hospital of Stomatology, Beijing, China. kqgang@bjmu.edu.cn.
Peking University · CNJinan Stomatological Hospital · CNYantai University · CN

Funding

National Key R&D Program of China 2018YFC0807303National Natural Science Foundation of China 61802330
6 · The paper itself

Abstract

objectivesTo develop an automatic segmentation method to segment the pulp chamber of first molars from 3D cone-beam-computed tomography (CBCT) images, and to estimate ages by calculated pulp volumes. MATERIALS AND

methodsPatients with CBCT scans were retrospectively identified. The age estimation was formulated as CBCT image segmentation using a coarse-to-fine strategy by integrated deep learning (DL) and level set (LS), followed by establishing a linear regression model. On the training data, DL model was trained for coarse segmentation. The validation set was to determine the optimal DL model, and a LS method established on it was to refine the coarse segmentation. On the testing data, the integrated DL and LS method was applied for pulp chamber segmentation, followed by volume calculation and age estimation. Statistical analysis was performed by Wilcoxon rank sum test to demonstrate gender difference in pulp chamber volume, and volume difference between maxillary and mandibular molars. Wilcoxon signed-rank test was adopted to compare true and estimated ages.

resultsA total of 180 CBCT studies were randomly divided into 37/10/133 patients for training, validation, and testing data, respectively. In the training and validation sets, the results showed high spatial overlaps between manual and automatic segmentation (dice = 87.8%). For the testing set, the estimated human ages were not significantly different with true human age (p = 0.57), with a correlation coefficient r = 0.74.

conclusionsAn integrated DL and LS method was able to segment pulp chamber of first molars from 3D CBCT images, and the derived pulp chamber volumes could effectively estimate the human ages.

Indexed as

Cone-Beam Computed TomographyDeep LearningImaging, Three-DimensionalAdolescentAdultAgedAge Determination by TeethChildDental Pulp CavityFemaleHumansLinear ModelsMaleMiddle AgedMolarRetrospective StudiesCone-beam–computed tomographyDeep learningFirst molarMedical image segmentationPulp chamber

Identifiers

PMID33185706
OpenAlexW3103262888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.