Evidence map›Paper›PMID 33185188›Full record

ArticleeLife2020

Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length.

Shanaya Shital Shah, Stella Hartono, Aurèle Piazza, Vanessa Som, William Wright, Frédéric Chédin, Wolf-Dietrich Heyer

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Mechanisms That Govern Recombinase Fidelity Control During Eukaryotic Homologous Recombination.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
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  13. Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Shanaya Shital ShahDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, United States.ORCID 0000-0002-2881-2794
Stella HartonoDepartment of Molecular and Cellular Biology, University of California, Davis, Davis, United States.
Aurèle PiazzaDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, United States.ORCID 0000-0002-7722-0955
Vanessa SomDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, United States.
William WrightDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, United States.
Frédéric ChédinDepartment of Molecular and Cellular Biology, University of California, Davis, Davis, United States.
Wolf-Dietrich HeyerDepartment of Microbiology and Molecular Genetics, University of California, Davis, Davis, United States.ORCID 0000-0002-7774-1953
University of California, Davis · USMammoth Biosciences (United States) · USUniversité Claude Bernard Lyon 1 · FR

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
RECOMBINATIONAL MECHANISMS OF DNA REPAIR IN EUKARYOTESR01GM058015 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI HEYER, WOLF-DIETRICH · 2000 to 2025
$8.8M
Regulation of Recombinational DNA RepairR01CA092276 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI HEYER, WOLF-DIETRICH · 2001 to 2020
$5.2M
Genomic profiling of pathological R-loop formation in human diseases.R01GM120607 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEDIN, FREDERIC LOUIS · 2016 to 2019
$1.2M
NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA092276NIGMS NIH HHS R01 GM058015NIGMS NIH HHS R01 GM120607
6 · The paper itself

Abstract

Displacement loops (D-loops) are critical intermediates formed during homologous recombination. Rdh54 (a.k.a. Tid1), a Rad54 paralog in

Indexed as

DNA, FungalDNA HelicasesDNA RepairDNA Repair EnzymesDNA TopoisomerasesGene Expression Regulation, FungalMutationRad51 RecombinaseSaccharomyces cerevisiae ProteinsDNA, FungalDNA HelicasesDNA Repair EnzymesDNA TopoisomerasesRAD51 protein, S cerevisiaeRad51 RecombinaseRAD54 protein, S cerevisiaeRDH54 protein, S cerevisiaeSaccharomyces cerevisiae Proteinschromosomesdsb repairgene expressiongenome stabilityrecombinationS. cerevisiae

Identifiers

PMID33185188
PMCPMC7695457
OpenAlexW3099314028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.