Evidence map›Paper›PMID 33185169›Full record

ReviewCurrent cardiology reviews2021

Common Comorbidities that Alter Heart Failure Prognosis - Shaping New Thinking for Practice.

Pupalan Iyngkaran, Merlin Thomas, John D Horowitz, Paul Komesaroff, Michael Jelinek, David L Hare

Open access · greenAbstract readReview
In one paragraph

Review in Current cardiology reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. HLM Staging and Treatment Benefit of SGLT2i Across Heart Failure Severity.Journal of cardiovascular development and disease · 2026
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Pupalan IyngkaranDepartment of Cardiology, Heart West Institute, Werribee Mercy Sub School, School of Medicine, Notre Dame University, Notre Dame, IN 46556, United States.
Merlin ThomasDepartment of Biochemistry, Biochemistry of Diabetes Complications, Monash University, Melbourne, Australia.
John D HorowitzDepartment of Cardiology, University of Adelaide, Adelaid, Australia.
Paul KomesaroffDepartment of Endocrinology, Monash University, Melbourne, Australia.
Michael JelinekDepartment of Cardiology, University of Melbourne, St. Vincent's Hospital, Melbourne, Australia.
David L HareDepartment of Cardiology, Cardiovascular Research, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.
Monash University · AUThe University of Melbourne · AUThe University of Adelaide · AUUniversity of Notre Dame · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

At least half of all heart failure (CHF) patients will have a comorbidity that could be undertreated, requires additional speciality input and/or polypharmacy. These patients are then at risk of iatrogenic and disease-related complications and readmissions if not closely supervised. Common comorbidities of relevance are cardiorenal and cardiometabolic syndromes (DM, obesity, OSA), chronic airways disease, elderly age, and accompanying pharmacotherapies. The structure of community practice often leaves primary, speciality, and allied health care in silos. For example, cardiology speciality training in Australia creates excellent sub-specialists to deliver diagnostic and therapeutic advances. A casualty of this process has been the gradual alienation of general cardiology toward general internal medical specialists and primary care practitioners. The consequences are largely noticed in community practice. The issue is compounded by suboptimal communication of information. This review explores these issues from a cardiology sub-speciality lens; firstly cross speciality areas that are important for cardiologists to maintain their skill, and finally, to obtain a brief overview of disease management and identify game-changing common denominators such as endothelial dysfunction and self-management.

Indexed as

CardiologyHeart FailureAgedAustraliaComorbidityHumansPrognosiscardiometabolic syndrome.cardiovascular diseaseComorbiditycongestive heart failuredisease managementmetabolically healthy obesityobesityobesity paradoxperformance markersprocess of carespecialist training

Identifiers

PMID33185169
PMCPMC8950452
OpenAlexW3098438492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.