Evidence map›Paper›PMID 33184835›Full record

ArticleJournal of the American Geriatrics Society2021

Racial/Ethnic Differences in Health-Related Quality of Life in Persons With and Without Dementia.

Eleanor Hayes-Larson, Taylor M Mobley, Andrea Gilmore-Bykovskyi, Crystal Shaw, Arun Karlamangla, Jennifer J Manly, Elizabeth Rose Mayeda

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

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  16. Lack of Any Caregiving for Those with Dementia.Journal of Alzheimer's disease : JAD · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Eleanor Hayes-LarsonDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
Taylor M MobleyDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
Andrea Gilmore-BykovskyiSchool of Nursing and Alzheimer's Disease Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Crystal ShawDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
Arun KarlamanglaDepartment of Geriatrics, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Jennifer J ManlyTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York City, New York, USA.
Elizabeth Rose MayedaDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
UCLA Health · USUniversity of California, Los Angeles · USColumbia University · USUniversity of Wisconsin–Madison · US

Funding

Wisconsin Alzheimer's Disease Research CenterP30AG062715 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Barbara Brigitta Bendlin · 2019 to 2026
$34.5M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Martha Jane Bailey · 2016 to 2026
$6.9M
Novel Approaches to Identifying and Engaging Disadvantaged Patients with Alzheimer’s Disease (AD) in Clinical ResearchK76AG060005 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI GILMORE-BYKOVSKYI, ANDREA L · 2018 to 2022
$1.1M
Racial Disparities in Alzheimer's Disease and Related Dementias: The Role of Blood Pressure Throughout AdulthoodR00AG053410 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYEDA, ELIZABETH ROSE · 2018 to 2020
$710k
NIA NIH HHS K76 AG060005NIA NIH HHS P30 AG062715NIA NIH HHS R00 AG053410NIA NIH HHS R00AG053410, K76AG060005NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

BACKGROUND/

objectivesGiven the lack of effective pharmacologic strategies to prevent, slow, or reverse dementia progression, maximizing quality of life (QOL) is a major priority for persons living with dementia. Despite well-documented racial/ethnic disparities in dementia incidence and prevalence, it is unknown whether there are racial/ethnic disparities in QOL among persons with dementia. The objective of this study was to determine if there are racial/ethnic differences in poor health-related quality of life (HRQOL) among persons with and without dementia in a nationally-representative cohort.

designRepeated measures cross-sectional analysis of a prospective cohort study.

settingUnited States nationally-representative National Health and Aging Trends Study (2011-2018).

participantsNon-nursing home-dwelling Black, Latino, and white adults age 65+ (n = 10,886). MEASUREMENTS: We estimated racial/ethnic differences in five dichotomous indicators of poor HRQOL (depressive and anxiety symptoms, self-rated health, pain, and physical functional limitations), stratified by dementia status (probable, possible, none). We used generalized estimating equations to estimate prevalence ratios (PRs) and differences, and marginal standardization to estimate prevalence.

resultsGenerally, Blacks and Latinos reported higher prevalence of poor HRQOL compared with whites. The largest differences were observed for self-rated health, and Latino-white differences were slightly larger compared to Black-white differences. PRs were larger among those with no dementia. For example, the Black versus white PRs for poor self-rated health were 1.93 (95% confidence interval (CI) = 1.82-2.04) among the no dementia group and 1.21 (95% CI = 1.12-1.31) among the probable dementia group; Latino versus white PRs for these comparisons were 2.39 (2.21-2.59) and 1.48 (1.35-1.62), respectively. Prevalence differences also showed racial/ethnic differences, but these were similar across dementia statuses.

conclusionsWe observed racial/ethnic disparities in poor HRQOL, showing greater unmet clinical needs among Black and Latino versus white older adults. Relative disparities were smaller in those with dementia, but absolute magnitudes of disparities were similar by dementia status.

Indexed as

Health Status DisparitiesQuality of LifeAgedAged, 80 and overAgingBlack or African AmericanCase-Control StudiesCross-Sectional StudiesDementiaFemaleHispanic or LatinoHumansMalePhysical Functional PerformanceProspective StudiesUnited Statesdementiaquality of liferacial/ethnic disparities

Identifiers

PMID33184835
PMCPMC7969393
OpenAlexW3102941328

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.