ReviewEuropean journal of pediatrics2021
Perinatal COVID-19: review of current evidence and practical approach towards prevention and management.
Review in European journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis.European journal of obstetrics, gynecology, and reproductive biology · 2021Pooled it
- Helios expression in naive CD4+ T cells decreases from neonates to older adults.Clinical and experimental immunology · 2026Article
- Laboratory changes and clinical correlates of disease severity in hospitalized pregnant women with COVID-19.Annals of medicine and surgery (2012) · 2025Article
- Listening to the women's experience of perinatal domestic violence during the COVID-19 pandemic: a qualitative content analysis.BMC pregnancy and childbirth · 2025Article
- The impact of SARS-CoV-2 infection on vaccinated versus unvaccinated pregnant women: a retrospective cohort study.BMC pregnancy and childbirth · 2025Observational
- Differentiating Viral from Bacterial Pneumonia in Children: The Diagnostic Role of Lung Ultrasound-A Prospective Observational Study.Diagnostics (Basel, Switzerland) · 2024Article
- Tiny Lungs, Big Differences: Navigating the Varied COVID-19 Landscape in Neonates vs. Infants via Biomarkers and Lung Ultrasound.Biomedicines · 2024Article
- The Status and Influencing Factors of COVID-19 Vaccination for 3-7-Year-Old Children Born Prematurely [Letter].Patient preference and adherence · 2024Article
- Pandemic-induced healthcare shifts: an observational analysis of maternal and neonatal outcomes in adolescent pregnancies.Frontiers in medicine · 2024Article
- COVID-19: the possibility, ways, mechanisms, and interruptions of mother-to-child transmission.Archives of gynecology and obstetrics · 2023Review
- Characterization of SARS-CoV-2 antibodies in human milk from 21 women with confirmed COVID-19 infection.Pediatric research · 2023Article
- Evaluation of clinical manifestations of coronavirus delta variant in neonates admitted to a hospital in northern Iran during the sixth wave: A case series.Journal of neonatal nursing : JNN · 2023Article
- Cross-Sectional Survey of Views on COVID-19 and Its Vaccines Among Pregnant Women.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023Article
- Perinatal Outcome in Maternal COVID-19 infection at a Tertiary care Institute- A cross Sectional Study.Journal of obstetrics and gynaecology of India · 2023Article
- COVID-19 Disease in Under-5 Children: Current Status and Strategies for Prevention including Vaccination.Vaccines · 2023Review
- Risks and Preventions for Pregnant Women and Their Preterm Infants in a World with COVID-19: A Narrative Review.Vaccines · 2023Review
- Screening for coronavirus disease 2019 in pregnant women admitted for delivery: an observational study.Revista da Associacao Medica Brasileira (1992) · 2023Observational
- COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy.Translational research : the journal of laboratory and clinical medicine · 2023Review
- Article
- PERINATAL ASPECTS OF SARS-CoV-2 INFECTION DURING PREGNANCY: A POTENTIAL CAUSE FOR CONCERN.Acta clinica Croatica · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical spectrum of the perinatal COVID-19 and prospective data on neonatal outcomes remains largely unexplored. Most of the existing literature is in the form of case series or single-centre experience. In this review, we aim to summarize available literature on the clinical spectrum of COVID-19 in neonates and mothers and suggest a practical approach towards management of clinical scenarios. This review explores the clinical characteristics and outcomes of COVID-19 in neonates born to mothers who were detected with the virus during the pregnancy. We conducted a comprehensive search of PubMed, Google Scholar and Cochrane Database of Systematic Review between November 2019 and June 2020 and screened articles related to perinatal COVID-19. This review included 786 mothers, among which 64% (504) were delivered by caesarian section. There were 3 still births and 107 (14%) were delivered preterm. Out of 793 neonates born, 629 neonates (79%) were tested after birth. The commonest symptom in neonates was respiratory distress. Respiratory support was needed in 60 neonates (7.6%), with 14 babies needing mechanical ventilation (1.8%), 25 needing non-invasive ventilation and 21 needing nasal oxygen. Only 35 of the 629 tested neonates (5.5%) were positive for COVID-19. Of the 35 positive neonates, 14 (40%) were symptomatic. The COVID-19 seems to have favourable neonatal outcomes. Majority of neonates are asymptomatic. Respiratory distress is the most common manifestation. What is known: •COVID-19 affects all ages. •Neonatal disease is usually mild. What is new: •Vertical transmission is a possible route of infection in neonates. •Breast milk and skin-to-skin contact are safe in COVID-19-infected mothers if performed with appropriate use of precautions such as hand and breast hygiene and masking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.