ArticleInternational orthopaedics2021
Comparison between osteosynthesis with interlocking nail and minimally invasive plating for proximal- and middle-thirds of humeral shaft fractures.
Article in International orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Humeral shaft fracture: systematic review of non-operative and operative treatment.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Intraoperative evaluation of rotational alignment in minimally invasive plate osteosynthesis for humeral shaft fractures using combined fluoroscopic and endoscopic assistance: surgical technique, clinical outcomes, and literature review.Archives of orthopaedic and trauma surgery · 2026Review
- Outcomes of Proximal Humeral Fracture Fixation Using Minimally Invasive Plate Osteosynthesis: A Prospective Clinical and Radiographic Study.Journal of orthopaedic case reports · 2025Article
- Helical plating yields better outcomes than intramedullary nailing or long straight lateral plating for humeral shaft fractures extending to the proximal humerus.Journal of orthopaedic surgery and research · 2025Article
- Comparative efficacy of Nice knot versus lag screw in augmenting locking plate fixation for comminuted clavicular fractures: a retrospective cohort study.BMC musculoskeletal disorders · 2025Article
- Review
- 3D printing assisted MIPO for treatment of complex middle-proximal humeral shaft fractures.BMC musculoskeletal disorders · 2024Article
- Ultrasound-guided preoperative localization of radial nerve in the treatment of extra-articular distal humeral shaft fractures.BMC musculoskeletal disorders · 2022Article
- Comparison of three different surgical treatment methods in humeral shaft fractures.The Pan African medical journal · 2022Article
- Assessment of Shoulder Function after Internal Fixation of Humeral Diaphyseal Fractures in Young Adults: A Prospective Comparative Study.Advances in orthopedics · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOptions for the treatment of proximal- and middle-thirds of humeral shaft fractures include intramedullary interlocking nail (IMN) and minimally invasive plate osteosynthesis (MIPO). However, whether IMN provides better clinical outcomes than MIPO surgical technique still remains unclear. This study was designed to compare clinical outcomes of the IMN with MIPO technique for the treatment of proximal- and middle-thirds of humeral shaft fractures.
methodA retrospective cohort analysis of 55 proximal- and middle-thirds of humeral shaft fractures surgically treated using IMN (n = 25) or MIPO (n = 30) from January 2012 to January 2016. Peri-operative and follow-up data (a minimum of 1 year) of the patients (aged from 18 to 56 years) were collected. Operative time, union time, VAS scores, surgery-related complications, and implant removal rate were compared between the two groups in this study. Besides, the functional outcomes were evaluated using the Rating Scale of American Shoulder and Elbow Surgeons' Form (ASES) and Mayo Elbow Performance Score System (MEPS).
resultWe found significantly shorter operative time and much less blood loss in IMN group, and lower VAS scores in the IMN group after surgery at first and third months but not at the sixth month. Complication rate was found to be relatively higher in the MIPO group when compared to the IMN group. No significant difference was observed between these two groups regarding ASES and MEPS scores. Three patients in the MIPO group suffered iatrogenic radial nerve injury and recovered after four to five months later. No implant failures occurred in either group.
conclusionIntramedullary interlocking nail seemed to be superior to minimally invasive plate osteosynthesis in the treatment of proximal- and middle-thirds of humeral shaft fractures due to shorter operative time and union time, less early post-operative pain, and fewer complications. The intramedullary interlocking nail could be considered a better surgical option for the management of proximal middle humeral fractures, though it may also depend on the surgeons' skills and learning curve. Further in-depth prospective studies are in great need to verify our conclusion.
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