ArticleAmerican journal of epidemiology2021
Depression, Anxiety, and Self-Directed Violence in Women With Endometriosis: A Retrospective Matched-Cohort Study.
Article in American journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06996340 (Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization), which is not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of White Noise on Pain, Anxiety and Comfort During in Invitro Fertilization: a Randomized Controlled Trial
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- "We adjusted for race": now what? A systematic review of utilization and reporting of race in American Journal of Epidemiology and Epidemiology, 2020-2021.Epidemiologic reviews · 2023Pooled it
- The impact of endometriosis on depressive and anxiety symptoms and quality of life: a systematic review.Frontiers in public health · 2023Pooled it
- Endometriosis and COVID-19: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022Pooled it
- Selected Parameters of the Mental State of Women with Endometriosis-A Systematic Review.Journal of clinical medicine · 2026Review
- Factors Influencing Fear of Progression in Endometriosis: A Path Analysis Using the Common-Sense Model.Journal of multidisciplinary healthcare · 2026Article
- Multimodal large language models for women's reproductive mental health.Archives of women's mental health · 2025Review
- The overlooked link between reproductive system disorders and depression: a cohort study in 2 million women.Psychological medicine · 2025Article
- Assessment of the Impact of Chronic Pain on the Prevalence of Depressive Disorders in Patients with Endometriosis.Diseases (Basel, Switzerland) · 2025Article
- Comorbidity analysis and clustering of endometriosis patients using electronic health records.Cell reports. Medicine · 2025Article
- WERF Endometriosis Phenome and Biobanking Harmonisation Project for Experimental Models in Endometriosis Research (EPHect-EM-Pain): methods to assess pain behaviour in rodent models of endometriosis.Molecular human reproduction · 2025Review
- Predictors of anxiety in endometriosis patients.Archives of gynecology and obstetrics · 2025Article
- Self-inflicted chronic laparoscopic wounds in endometriosis-unveiling major depressive disorder: a case report.AJOG global reports · 2025Article
- Plasma metabolites associated with endometriosis in adolescents and young adults.Human reproduction (Oxford, England) · 2025Article
- Burden of somatic morbidity associated with a surgically verified diagnosis of endometriosis at a young age: a register-based follow-up cohort study in Finland.Human reproduction (Oxford, England) · 2025Article
- Relationship between endometriosis and mental health. A systematic review and meta-analysis.Archives of medical science : AMS · 2025Review
- Analysis of risk factors for postoperative anxiety and depression in endometriosis patients with reproductive intention.World journal of psychiatry · 2024Article
- The impact of vitamin D treatment on pregnancy rate among endometriosis patients: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2024Review
- Risk factors and prediction model for sub-threshold depression in young and middle-aged breast cancer patients.American journal of translational research · 2024Article
- Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities.Human reproduction update · 2023Review
- Genomic characterisation of the overlap of endometriosis with 76 comorbidities identifies pleiotropic and causal mechanisms underlying disease risk.Human genetics · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to compare the incidence of mental health outcomes in women in the United States with and without documented endometriosis. In a retrospective matched-cohort study using administrative health claims data from Optum's Clinformatics DataMart from May 1, 2000, through March 31, 2019, women aged 18-50 years with endometriosis (n = 72,677), identified by International Classification of Disease diagnosis codes (revisions 9 or 10), were matched 1:2 on age and calendar time to women without endometriosis (n = 147,251), with a median follow-up of 529 days (interquartile range, 195, 1,164). The rate per 1,000 person-years of anxiety, depression, and self-directed violence among women with endometriosis was 57.1, 47.7, and 0.9, respectively. Comparing women with endometriosis to those without, the adjusted hazard ratios and 95% confidence intervals were 1.38 (1.34, 1.42) for anxiety, 1.48 (1.44, 1.53) for depression, and 2.03 (1.60, 2.58) for self-directed violence. The association with depression was stronger among women younger than 35 years (P for heterogeneity < 0.01). Risk factors for incident depression, anxiety, and self-directed violence among women with endometriosis included endometriosis-related pain symptoms and prevalence of other chronic conditions associated with pain. The identification of risk factors for mental health conditions among women with endometriosis may improve patient-centered disease management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.