Evidence map›Paper›PMID 33184607›Full record

ArticleRegenerative engineering and translational medicine2020

Regulation of Stem Cell Function in an Engineered Vocal Fold-Mimetic Environment.

Aidan B Zerdoum, Pooya Saberi, Alexander J Stuffer, Dakota J Kelly, Randall L Duncan, Luc Mongeau, Xinqiao Jia

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Regenerative engineering and translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Bioreactors for Vocal Fold Tissue Engineering.Tissue engineering. Part B, Reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Aidan B ZerdoumDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Pooya SaberiDepartment of Mechanical Engineering, McGill University, Montreal, Quebec, H3A 0C3, Canada.
Alexander J StufferDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Dakota J KellyDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
Randall L DuncanDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
Luc MongeauDepartment of Mechanical Engineering, McGill University, Montreal, Quebec, H3A 0C3, Canada.
Xinqiao JiaDepartment of Biomedical Engineering, University of Delaware, Newark, DE 19716, USA.
DuPont (United States) · USMcGill University · CAUniversity of Delaware · USBiotechnology Institute · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI MELINDA K DUNCAN · 2012 to 2026
$67.2M
A Hydrogel-Based Cellular Model of the Human Vocal FoldR01DC014461 · NIDCD · UNIVERSITY OF DELAWARE · PI Xinqiao Jia · 2016 to 2026
$6.2M
Pilot Research Subproject ProgramP30GM110758 · NIGMS · UNIVERSITY OF DELAWARE · PI PATEL, SANDEEP · 2014 to 2018
$5.8M
Zeiss LSM710 Inverted Confocal MicroscopeS10OD016361 · OD · UNIVERSITY OF DELAWARE · PI CAPLAN, JEFFREY L · 2015 to 2015
$444k
NIDCD NIH HHS R01 DC014461NIGMS NIH HHS P20 GM103446NIGMS NIH HHS P30 GM110758NIH HHS S10 OD016361
6 · The paper itself

Abstract

Human mesenchymal stem cells (hMSCs) have been proposed as therapeutic cells for the treatment of vocal fold (VF) scarring. Although functional recovery was observed in animal models after stem cell injection, it is not clear how injected stem cells interact locally with the extracellular matrix (ECM) of the lamina propria (LP) and how such interactions affect stem cell behaviors to improve function. Herein, we developed an

Indexed as

bioreactorfibrosisMesenchymal stem cellsvibrationvocal fold

Identifiers

PMID33184607
PMCPMC7654964
OpenAlexW3002932279

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.