Evidence map›Paper›PMID 33184512›Full record

ArticleNature2021

Phenotypic variation of transcriptomic cell types in mouse motor cortex.

Federico Scala, Dmitry Kobak, Matteo Bernabucci, Yves Bernaerts, Cathryn René Cadwell, Jesus Ramon Castro, Leonard Hartmanis, Xiaolong Jiang, Sophie Laturnus, Elanine Miranda and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 235 papers.

0numbers the graph read from it
0cells of the map it votes in
235citing papers in PubMed
23.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

235 citing papers in PubMed, 390 citations in OpenAlex.

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175 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Federico Scala *Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.
Dmitry Kobak *Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-5639-7209
Matteo BernabucciCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0003-4458-117X
Yves BernaertsInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.
Cathryn René CadwellDepartment of Pathology, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-1963-8285
Jesus Ramon CastroCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.
Leonard HartmanisDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Xiaolong JiangCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0001-8066-1383
Sophie LaturnusInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.
Elanine MirandaCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.
Shalaka MulherkarDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Zheng Huan TanCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA.
Zizhen YaoAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-9361-5607
Hongkui ZengAllen Institute for Brain Science, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0326-5878
Rickard SandbergDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-6473-1740
Philipp BerensInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany. philipp.berens@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-0199-4727
Andreas S ToliasCenter for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX, USA. astolias@bcm.edu.ORCID http://orcid.org/0000-0002-4305-6376
Baylor College of Medicine · USAllen Institute for Brain Science · USKarolinska Institutet · SEUniversity of Tübingen · DEBernstein Center for Computational Neuroscience Tübingen · DEMax Planck Institute for Intelligent Systems · DEUniversity of California, San Francisco · US

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI ANDERSON, DAVID J, PACHTER, LIOR S · 2017 to 2021
$64.7M
VISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8M
VISUAL SCIENCEST32EY007001 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$3.7M
Deciphering the building blocks of hippocampal circuitsR01MH109556 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI SANDBERG, RICKARD, TOLIAS, ANDREAS · 2017 to 2021
$3.3M
Deciphering the building blocks of the macaque prefrontal cortical microcircuitR01MH120404 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI JIANG, XIAOLONG · 2019 to 2023
$2.0M
Multi-Cellular Analysis of the Retinal NetworkR01EY033492 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Xiaolong Jiang, Samuel M Wu · 2022 to 2026
$2.0M
Deciphering the transcriptomic signatures, physiology, and connectivity of the specialized morphotypes in macaque insular cortexR01MH122169 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI JIANG, XIAOLONG · 2020 to 2024
$1.2M
NEI NIH HHS P30 EY002520NEI NIH HHS R01 EY033492NEI NIH HHS T32 EY007001NIMH NIH HHS R01 MH109556NIMH NIH HHS R01 MH120404NIMH NIH HHS R01 MH122169NIMH NIH HHS U19 MH114830
6 · The paper itself

Abstract

Cortical neurons exhibit extreme diversity in gene expression as well as in morphological and electrophysiological properties

Indexed as

Gene Expression ProfilingTranscriptomeAnimalsAtlases as TopicFemaleGABAergic NeuronsGlutamatesLysineMaleMiceMotor CortexNeuronsOrgan SpecificityPatch-Clamp TechniquesPhenotypeSequence Analysis, RNAbiocytinGlutamatesLysine

Identifiers

PMID33184512
PMCPMC8113357
OpenAlexW3106117005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.