Observational studyPediatric research2021
Post-hemorrhagic ventricular dilatation: inter-observer reliability of ventricular size measurements in extremely preterm infants.
Observational study in Pediatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Intervention at an early threshold for post-hemorrhagic ventricular dilatation in preterm infants: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2024Pooled it
- Evaluation of nationwide variation in post-haemorrhagic ventricular dilatation management following national guideline implementation in the Netherlands.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Implementation of an early intervention strategy for post hemorrhagic ventricular dilatation in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2026Observational
- Neurodevelopmental impairment in preterm infants following progressive post-hemorrhagic ventricular dilatation.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Cranial Ultrasonography-Standards in Diagnosis of Intraventricular Hemorrhage and Ventricular Dilatation in Premature Neonates.Children (Basel, Switzerland) · 2025Review
- Imaging biomarkers for detection and longitudinal monitoring of ventricular abnormalities from birth to childhood.World journal of radiology · 2025Review
- Predicting preterm post-hemorrhagic ventricular dilatation and the need for biomarkers.Pediatric research · 2025Article
- Prediction of post-hemorrhagic ventricular dilatation trajectory using a growth mixture model in preterm infants.Pediatric research · 2025Article
- Prediction of short- and long-term outcomes using pre-operative ventricular size in infants with post-hemorrhagic ventricular dilation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Ratios of head circumference to ventricular size vary over time and predict eventual need for CSF diversion in intraventricular hemorrhage of prematurity.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Neuroimaging of Germinal Matrix and Intraventricular Hemorrhage in Premature Infants.Journal of Korean Neurosurgical Society · 2023Article
- Hemodynamic Quality Improvement Bundle to Reduce the Use of Inotropes in Extreme Preterm Neonates.Paediatric drugs · 2022Article
- Degree of ventriculomegaly predicts school-aged functional outcomes in preterm infants with intraventricular hemorrhage.Pediatric research · 2022Article
- Fronto-temporal horn ratio: yet another marker of ventriculomegaly?Pediatric research · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-hemorrhagic ventricular dilatation (PHVD) in preterm infants can be assessed with ventricular size indices from cranial ultrasound. We explored inter-observer reliability of these indices for prediction of severe PHVD.
methodsFor all 139 infants with IVH, serial neonatal ultrasound at 3 time points (days 4-7, day 14, 36 weeks PMA) were assessed independently by 3 observers with differing levels of training/experience. Ventricular index (VI), anterior horn width (AHW), and fronto-temporal horn ratio (FTHR) were measured and used to diagnose PHVD. For all, inter-observer reliability and predictive values for receipt of surgical intervention were calculated.
resultsInter-observer reliability for all observers varied from poor to excellent, with higher reliability for VI/AHW (ICC 0.49-0.84/0.51-0.81) than FTHR (0.41-0.82), particularly from the second week. Good-excellent inter-expertise reliability was found between observers with ample experience/training (0.65-0.99), particularly for VI and AHW, while poor-moderate when comparing with an inexperienced observer (0.28-0.88). Slightly higher predictive value for PHVD intervention (n = 12) was found for AHW (AUC 0.86-0.96) than for VI and FTHR (0.80-0.96/0.80-0.95).
conclusionsAHW and VI are highly reproducible in experienced hands compared to FTHR, with AHW from the second week onwards being the strongest predictor for receiving surgical intervention for severe PHVD. AHW may aid in early PHVD diagnosis and decision-making on intervention. IMPACT: While ventricular size indices from serial cUS are superior to clinical signs of increased intracranial pressure to assess PHVD, questions remained on their inter-observer reproducibility and reliability to predict severity of PHVD. AHW and VI are highly reproducible when performed by experienced clinicians. AHW from the second week of birth is the strongest predictor of PHVD onset and severity. AHW, combined with VI, may aid in early PHVD diagnosis and decision-making on need for surgical intervention. Consistent use of these indices has the potential to improve PHVD management and therewith the long-term outcomes in preterm infants.
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