Evidence map›Paper›PMID 33184453›Full record

ArticleEuropean journal of clinical nutrition2021

Iodine status of pregnant women with obesity from inner city populations in the United Kingdom.

Jessica Farebrother, Kathryn V Dalrymple, Sara L White, Carolyn Gill, Anna Brockbank, John H Lazarus, Keith M Godfrey, Lucilla Poston, Angela C Flynn

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Iodine nutrition among pregnant women in the Faroe Islands.The British journal of nutrition · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Iodine status in pregnant women and infants in Finland.European journal of nutrition · 2022
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jessica FarebrotherDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK. jessica.farebrother@hest.ethz.ch.ORCID http://orcid.org/0000-0003-1005-139X
Kathryn V DalrympleDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Sara L WhiteDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Carolyn GillDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Anna BrockbankDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
John H LazarusCardiff School of Medicine, Cardiff University, Cardiff, Wales, UK.
Keith M GodfreyMRC Lifecourse Epidemiology Unit and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.ORCID http://orcid.org/0000-0002-4643-0618
Lucilla PostonDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
Angela C FlynnDepartment of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK.
King's College London · GBCardiff University · GBUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

British Heart Foundation FS/09/057/27957British Heart Foundation FS/17/71/32953British Heart Foundation PG/11/22/28800British Heart Foundation (BHF) RG/15/17/3174Department of Health RP-PG-0407-10452DH | National Institute for Health Research (NIHR) NF-SI-0515-10042EC | Erasmus+ 573651-EPP-1-2016-1-DE-EPPKA2-CBHE-JPMedical Research Council MC_PC_21001Medical Research Council MC_PC_21003Medical Research Council MR/L002477/1RCUK | Medical Research Council (MRC) MC_UU_12011/4RCUK | Medical Research Council (MRC) MR/R019177/1
6 · The paper itself

Abstract

BACKGROUND/

objectivesIodine is essential for foetal neurodevelopment and growth. Requirements increase in pregnancy to support increased thyroid hormone synthesis for maternal and foetal requirements, and for foetal transfer. Iodine deficiency in pregnancy is widely reported, and obesity has been associated with sub-optimal thyroid function. We evaluated iodine status and its relation with birthweight in a secondary analysis of pregnant women with obesity from multi-ethnic inner-city settings who participated in the UK Pregnancies Better Eating and Activity trial (UPBEAT). SUBJECTS/

methodsIodine and creatinine concentrations were evaluated in spot urine samples in the second (15

resultsMedian (IQR) UIC and UI/Cr in the second trimester of pregnancy were 147 µg/L (99-257) and 97 µg/g (59-165), respectively. An UI/Cr <150 μg/g was observed in 70% of women. Compared to women with UI/Cr >150 µg/g, there was a trend for women with UI/Cr <150 µg/g to deliver infants with a lower birthweight (β = -60.0 g; 95% CI -120.9 to -1.01, P = 0.05).

conclusionsIodine status of pregnant women with obesity from this cohort of UK women was suboptimal. Lower iodine status was associated with lower birthweight.

Indexed as

IodineFemaleHumansNutritional StatusObesityPregnancyPregnant PeopleUnited KingdomIodine

Identifiers

PMID33184453
OpenAlexW3098086732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.