ArticleScientific reports2020
Hemocytes released in seawater act as Trojan horses for spreading of bacterial infections in mussels.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- External immune sentinels in the seawater ecosystem: the specialization of bivalve hemocytes.Frontiers in immunology · 2026Article
- Gene expression in soft-shell clam (Mya arenaria) transmissible cancer reveals survival mechanisms during host infection and seawater transfer.PLoS genetics · 2025Article
- Dynamics ofFrontiers in immunology · 2025Article
- Marine transmissible cancer navigates urbanized waters, threatening spillover.Proceedings. Biological sciences · 2024Article
- Applying the concept of liquid biopsy to monitor the microbial biodiversity of marine coastal ecosystems.ISME communications · 2022Article
- Species- and site-specific circulating bacterial DNA in Subantarctic sentinel mussels Aulacomya atra and Mytilus platensis.Scientific reports · 2022Article
- Survival and Detection of Bivalve Transmissible Neoplasia from the Soft-Shell ClamPathogens (Basel, Switzerland) · 2022Article
- Traits of a mussel transmissible cancer are reminiscent of a parasitic life style.Scientific reports · 2021Article
- Group phenotypic composition in cancer.eLife · 2021Review
- First description of a widespread Mytilus trossulus-derived bivalve transmissible cancer lineage in M. trossulus itself.Scientific reports · 2021Article
- Genotype data not consistent with clonal transmission of sea turtle fibropapillomatosis or goldfish schwannoma.Wellcome open research · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global warming has been associated with increased episodes of mass mortality events in invertebrates, most notably in bivalves. Although the spread of pathogens is one of multiple factors that contribute to such mass mortality events, we don't fully understand the pathophysiological consequences of sea warming on invertebrates. In this work, we show that in temperature stress conditions, circulating hemocytes in mussels leave the hemolymph to gain access to the intervalvar fluid before being released in seawater. External hemocytes can survive for several hours in seawater before entering other mussels. When infected by bacteria, externally-infected hemocytes can enter naive mussels and promote bacterial dissemination in the host. These results reveal the existence of a new opportunistic mechanism used by pathogens to disseminate in marine ecosystems. Such mechanisms may explain how thermal anomalies triggered by global warming can favor episodic mass mortality observed in recent years in marine ecosystem.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.