ArticleScientific reports2020
Synergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of biofunctionalaized silver nanoparticles.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 182 citations in OpenAlex.
- Fabrication of nitrofurantoin-loaded chitosan-silver nanoparticles for the treatment of urinary tract infections.Scientific reports · 2026Article
- Harnessing biogenic nanoparticles for combating antibiotic resistance: green synthesis, mechanistic insights, and biotechnological applications.Frontiers in bioengineering and biotechnology · 2026Review
- Phytochemical Profiling, Molecular Docking, ADMET Analysis ofACS omega · 2025Article
- Application of Composite Preservative Based on Moringa Leaf Flavonoids and Chitosan in the Preservation of Fruits and Vegetables.Food science & nutrition · 2025Article
- From Bacterial Extract to Breakthrough Therapy:Pharmaceutics · 2025Article
- Tailoring innovative silver nanoparticles for modern medicine: The importance of size and shape control and functional modifications.Materials today. Bio · 2025Review
- Antimicrobial, Quorum Sensing Inhibition, and Anti-Cancer Activities of Silver Nanoparticles Synthesized from Kenyan Bacterial Endophytes ofInternational journal of molecular sciences · 2025Article
- Biocompatible and Antibacterial Chemical Coatings on TiZr Dental Implants.Journal of functional biomaterials · 2025Article
- Microbial mediated silver nanoparticles enhance the potential of bioactive metabolites in the medicinal plantRSC advances · 2025Article
- Synergestic Protein-Green synthesized Nanoparticles Nanosystems: A Sustainable and Safe Approach for Cancer Theranostics.Nanotheranostics · 2025Review
- Nanosilver-Biopolymer-Silica Composites: Preparation, and Structural and Adsorption Analysis with Evaluation of Antimicrobial Properties.International journal of molecular sciences · 2024Article
- Eco-friendly green synthesis of silver nanoparticles from guajava leaves extract for controlling organophosphorus pesticides hazards, characterization, and in-vivo toxicity assessment.BMC pharmacology & toxicology · 2024Article
- The Highly Durable Antibacterial Gel-like Coatings for Textiles.Gels (Basel, Switzerland) · 2024Article
- Green Synthesized Chitosan Nanoparticles for Controlling Multidrug-ResistantInternational journal of molecular sciences · 2024Article
- Silver Nanoparticles-Chitosan Nanocomposites: A Comparative Study Regarding Different Chemical Syntheses Procedures and Their Antibacterial Effect.Materials (Basel, Switzerland) · 2024Article
- Research and Application of Chitosan Nanoparticles in Orthopedic Infections.International journal of nanomedicine · 2024Review
- Article
- Antimicrobial and antioxidant potential of the silver nanoparticles synthesized using aqueous extracts of coconut meat (Cocos nucifera L).Scientific reports · 2023Article
- Chlorhexidine-Silver Nanoparticle Conjugation Leading to Antimicrobial Synergism but Enhanced Cytotoxicity.Pharmaceutics · 2023Article
- Fabrication and Evaluation of Anticancer Potential of Eugenol Incorporated Chitosan-Silver Nanocomposites: In Vitro, In Vivo, and In Silico Studies.AAPS PharmSciTech · 2023Article
Corrections and comments
- Erratum issued
- Retracted
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study reports the synergistic antibacterial activity of biosynthesized silver nanoparticles (AgNPs) with the aid of a combination of chitosan and seaweed-derived polyphenols as a green synthetic route. Under optimum synthesis conditions, the rapid color change from yellowish to dark brown and UV-visible absorption peak at 425 confirmed the initial formation of AgNPs. DLS, TEM, XRD, and EDX analyses revealed the spherical shape of pure biogenic AgNPs with a mean diameter size of 12 nm ± 1.5 nm, and a face-centered cubic crystal structure, respectively. FTIR and TGA results indicated the significant contribution of chitosan and polyphenol components into silver ions bioreduction and thermal stability of freshly formed AgNPs. Long-term colloidal stability of AgNPs was obtained after 6-month storage at room temperature. The bio-prepared AgNPs possessed a negative surface charge with a zeta potential value of - 27 mV. In contrast to naked chemical silver nanoparticles, the green Ag nanosamples demonstrated the distinct synergistic antibacterial in vitro toward all selected human pathogens presumably due to the presence of high content of biomolecules on their surface. The results show that synergy between chitosan and polyphenol results in the enhancement of bactericidal properties of biogenic AgNPs. We also highlighted the underlying mechanism involved in AgNPs formation based on nucleophile-electrophile interaction.
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