Evidence map›Paper›PMID 33184150›Full record

ArticleDiabetes care2021

Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated

Pamela Bowman, Frances Mathews, Fabrizio Barbetti, Maggie H Shepherd, Janine Sanchez, Barbara Piccini, Jacques Beltrand, Lisa R Letourneau-Freiberg, Michel Polak, Siri Atma W Greeley and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Knowledge, Attitudes, and Practices in Neonatal Diabetes Mellitus Management: the JEnious-NeOnatal-DIabetes (JENODI) Survey.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
  7. Article
  8. Monogenic Familial Neonatal Diabetes in Preterm Infant WithThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025
    Article
  9. Review
  10. Neonatal diabetes mellitus around the world: Update 2024.Journal of diabetes investigation · 2024
    Review
  11. Insulin Delivery Technology for Treatment of Infants with Neonatal Diabetes Mellitus: A Systematic Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Growth and development in monogenic forms of neonatal diabetes.Current opinion in endocrinology, diabetes, and obesity · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Pamela BowmanExeter NIHR Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, U.K. p.bowman@exeter.ac.uk.ORCID 0000-0002-5241-7700
Frances MathewsExeter NIHR Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, U.K.
Fabrizio BarbettiDepartment of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0003-4687-980X
Maggie H ShepherdExeter NIHR Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, U.K.
Janine SanchezMiller School of Medicine, University of Miami, Miami, FL.
Barbara PicciniRegional Center for Pediatric Diabetes, Meyer University Children's Hospital, Florence, Italy.
Jacques BeltrandService d'Endocrinologie, Gynécologie et Diabétologie Pédaitrique, APHP Centre, Université de Paris, Paris, France.ORCID 0000-0002-3759-3490
Lisa R Letourneau-FreibergKovler Diabetes Center, The University of Chicago, Chicago, IL.
Michel PolakService d'Endocrinologie, Gynécologie et Diabétologie Pédaitrique, APHP Centre, Université de Paris, Paris, France.
Siri Atma W GreeleyKovler Diabetes Center, The University of Chicago, Chicago, IL.
Eamon RawlinsInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
Tarig BabikerInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
Nicholas J ThomasInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
Elisa De FrancoInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.ORCID 0000-0002-1437-7891
Sian EllardInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
Sarah E FlanaganInstitute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, U.K.
Andrew T HattersleyORCID 0000-0001-5620-473X
Neonatal Diabetes International Collaborative Group
University of Exeter · GBUniversity of Chicago · USUniversity of Miami · USInserm · FRMeyer Children's Hospital · ITUniversity of Rome Tor Vergata · IT

Funding

Pilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Matthew J Brady · 2013 to 2026
$20.9M
Monogenic Diabetes: Next Generation Diagnosis, Treatment and ComplicationsR01DK104942 · NIDDK · UNIVERSITY OF CHICAGO · PI GREELEY, SIRI ATMA W., PHILIPSON, LOUIS H. · 2016 to 2024
$4.7M
Diabetes UK 16/0005407Diabetes UK 19/0005971NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK104942Wellcome Trust 091985Wellcome Trust 105636
6 · The paper itself

Abstract

objectiveRESEARCH DESIGN AND

methodsWe studied all 24 individuals with

resultsLong-term data were obtained for 21 of 24 individuals (median follow-up 10.0 [range 4.1-13.2] years). Eighteen of 21 remained on sulfonylureas without insulin at the most recent follow-up. Glycemic control improved on sulfonylureas (presulfonylurea vs. 1-year posttransfer HbA

conclusionsSulfonylurea treatment of

Indexed as

Diabetes MellitusPotassium Channels, Inwardly RectifyingFollow-Up StudiesHumansHypoglycemic AgentsInfant, NewbornMutationSulfonylurea ReceptorsABCC8 protein, humanHypoglycemic AgentsPotassium Channels, Inwardly RectifyingSulfonylurea Receptors

Identifiers

PMID33184150
PMCPMC7783935
OpenAlexW3098100508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.