Evidence map›Paper›PMID 33183160›Full record

ArticleCirculation research2021

Shortening Velocity Causes Myosin Isoform Shift in Human Engineered Heart Tissues.

Ronald Ng, Lorenzo R Sewanan, Paul Stankey, Xia Li, Yibing Qyang, Stuart Campbell

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronald NgDepartment of Biomedical Engineering (R.N., L.R.S., P.S., X.L., S.C.), Yale University, New Haven, CT.
Lorenzo R SewananDepartment of Biomedical Engineering (R.N., L.R.S., P.S., X.L., S.C.), Yale University, New Haven, CT.
Paul StankeyDepartment of Biomedical Engineering (R.N., L.R.S., P.S., X.L., S.C.), Yale University, New Haven, CT.
Xia LiDepartment of Biomedical Engineering (R.N., L.R.S., P.S., X.L., S.C.), Yale University, New Haven, CT.
Yibing QyangYale Stem Cell Center (Y.Q.), Yale University, New Haven, CT.
Stuart CampbellDepartment of Biomedical Engineering (R.N., L.R.S., P.S., X.L., S.C.), Yale University, New Haven, CT.

Funding

Revealing Pathomechanisms of Mutant TPM1 Through a Hybrid Computational-Experimental ApproachR01HL136590 · NHLBI · YALE UNIVERSITY · PI STUART G CAMPBELL, William J Lehman · 2017 to 2026
$5.6M
Biomechanical Signaling in Human Familial Hypertrophic CardiomyopathyR01HL131940 · NHLBI · YALE UNIVERSITY · PI QYANG, YIBING · 2016 to 2019
$1.7M
NHLBI NIH HHS R01 HL131940NHLBI NIH HHS R01 HL136590
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DifferentiationMyocardial ContractionTissue EngineeringBioreactorsCardiac Pacing, ArtificialCell Culture TechniquesCells, CulturedHuman Embryonic Stem CellsHumansMyocytes, CardiacMyosin Heavy ChainsPhenotypeTime FactorsMyh6 protein, mouseMyh7 protein, mouseMyosin Heavy Chainscardiac outputheartmyosin heavy chainsstem cells

Identifiers

PMID33183160
PMCPMC7855774

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.