Evidence map›Paper›PMID 33183098›Full record

ArticleRenal failure2020

Value of the high-sensitivity troponin T assay for diagnosis of acute myocardial infarction in patients with and without renal insufficiency.

Cheng-Kai Hsu, I-Wen Wu, Yih-Ting Chen, Chia-Huei Peng, Yi-Ju Tseng, Yung-Chang Chen, Ming-Jui Hung, Yu-Cheng Kao

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Cheng-Kai HsuDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.ORCID https://orcid.org/0000-0002-6812-526X
I-Wen WuDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Yih-Ting ChenDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Chia-Huei PengDepartment of Pediatric Gastroenterology and Nutrition, Mackay Children's Hospital, Taipei, Taiwan.
Yi-Ju TsengDepartment of Information Management, Chang Gung University, Taoyuan, Taiwan.ORCID https://orcid.org/0000-0002-1814-5553
Yung-Chang ChenDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Ming-Jui HungCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Yu-Cheng KaoDepartments of Cardiology and Community Medicine Research Center, Chang Gung Memorial Hospital, Keelung.
Chang Gung University · TWChang Gung Memorial Hospital · TWKeelung Chang Gung Memorial Hospital · TWMackay Memorial Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac troponins are important markers for diagnosis of acute myocardial infarction (AMI) in general population; however, chronically-elevated troponins levels are often seen in patients with renal insufficiency, which reduce their diagnostic accuracy. The aim of our study was to access the diagnostic values of initial high-sensitive cardiac troponin T (hs-cTnT) and relative change of hs-cTnT for AMI in patients with and without renal insufficiency.

methodsCardiac care unit patients with elevated hs-cTnT levels in 2017-2018 were enrolled. Receiver operating characteristic (ROC) curves were used to evaluate initial hs-cTnT levels and relative changes after 3 h of enrollment for diagnosis of AMI in patients with estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m

resultsOf 359 patients, 240 patients had low eGFR, and 119 patients had normal eGFR. The area under the ROC curve (AUC) for the initial hs-cTnT levels was 0.58 (95% CI, 0.5-0.65,

conclusionsRelative changes in hs-cTnT levels had better diagnostic accuracy than initial hs-cTnT levels.

Indexed as

AgedAged, 80 and overArea Under CurveBiomarkersFemaleGlomerular Filtration RateHumansMaleMiddle AgedMyocardial InfarctionProspective StudiesRenal InsufficiencyROC CurveTroponin TBiomarkersTroponin TAcute myocardial infarction (AMI)chronic kidney disease (CKD)renal failuretroponin T

Identifiers

PMID33183098
PMCPMC7671591
OpenAlexW3099447495

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.