Evidence map›Paper›PMID 33182828›Full record

ReviewBiomolecules2020

Curcumin against Prostate Cancer: Current Evidence.

Deborah Termini, Danja J Den Hartogh, Alina Jaglanian, Evangelia Tsiani

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 159 citations in OpenAlex.

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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Deborah TerminiDepartment of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Danja J Den HartoghDepartment of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Alina JaglanianDepartment of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.ORCID 0000-0001-6946-3108
Evangelia TsianiDepartment of Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Brock University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a condition characterized by remarkably enhanced rates of cell proliferation paired with evasion of cell death. These deregulated cellular processes take place following genetic mutations leading to the activation of oncogenes, the loss of tumor suppressor genes, and the disruption of key signaling pathways that control and promote homeostasis. Plant extracts and plant-derived compounds have historically been utilized as medicinal remedies in different cultures due to their anti-inflammatory, antioxidant, and antimicrobial properties. Many chemotherapeutic agents used in the treatment of cancer are derived from plants, and the scientific interest in discovering plant-derived chemicals with anticancer potential continues today. Curcumin, a turmeric-derived polyphenol, has been reported to possess antiproliferative and proapoptotic properties. In the present review, we summarize all the in vitro and in vivo studies examining the effects of curcumin in prostate cancer.

Indexed as

Antineoplastic AgentsApoptosisCell ProliferationCurcuminGene Expression Regulation, NeoplasticHumansMaleProstatic NeoplasmsAntineoplastic AgentsCurcuminandrogen-insensitiveandrogen-sensitiveapoptosiscurcuminin vitroin vivopolyphenolproliferationprostate cancersurvival

Identifiers

PMID33182828
PMCPMC7696488
OpenAlexW3101741912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.