Evidence map›Paper›PMID 33182783›Full record

Observational studyNutrients2020

Fatty Acid Profile of Mature Red Blood Cell Membranes and Dietary Intake as a New Approach to Characterize Children with Overweight and Obesity.

Iker Jauregibeitia, Kevin Portune, Itxaso Rica, Itziar Tueros, Olaia Velasco, Gema Grau, Nerea Trebolazabala, Luis Castaño, Anna Vita Larocca, Carla Ferreri and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
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  12. Review
  13. Observational
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  15. CitrusNutrients · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Iker JauregibeitiaAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio, Spain.
Kevin PortuneAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio, Spain.
Itxaso RicaBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, 48903 Barakaldo, Spain.
Itziar TuerosAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio, Spain.ORCID 0000-0002-7609-5435
Olaia VelascoBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, 48903 Barakaldo, Spain.
Gema GrauBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, 48903 Barakaldo, Spain.
Nerea TrebolazabalaBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, 48903 Barakaldo, Spain.
Luis CastañoBiocruces Bizkaia Health Research Institute, Cruces University Hospital, CIBERDEM/CIBERER, UPV/EHU, 48903 Barakaldo, Spain.
Anna Vita LaroccaLipidomic Laboratory, Lipinutragen srl, Via di Corticella 181/4, 40128 Bologna, Italy.
Carla FerreriConsiglio Nazionale delle Ricerche, ISOF, Via Piero Gobetti 101, 40129 Bologna, Italy.ORCID 0000-0002-1359-0869
Sara ArranzAZTI, Food Research, Basque Research and Technology Alliance (BRTA), Parque Tecnológico de Bizkaia, Astondo Bidea, Edificio 609, 48160 Derio, Spain.ORCID 0000-0002-0411-9784

Funding

ALTERNATIVE PATHWAYS OF T CELL ACTIVATIONK08AR002017 · NIAMS · VANDERBILT UNIVERSITY · PI BYRD, VICTOR M · 1998 to 2002
$348k
Department of Environment: Territorial Planning: Agriculture and Fisheries of the Basque Country Government ELKARTEK 2017 and Innovation Fund 2017Department of Health of the Basque Government 2017222033: OBESIA 2016-2019INC (INTERNATIONAL NUT AND DRIED FRUIT COUNCIL) OBINUT project (2016(II)-R01).the Centre for the Development of Industrial Technology (CDTI) of the Spanish Ministry of Science and Innovation TECNOMIFOOD project (CER-20191010)
6 · The paper itself

Abstract

Obesity is a chronic metabolic disease of high complexity and of multifactorial origin. Understanding the effects of nutrition on childhood obesity metabolism remains a challenge. The aim of this study was to determine the fatty acid (FA) profile of red blood cell (RBC) membranes as a comprehensive biomarker of children's obesity metabolism, together with the evaluation of their dietary intake. An observational study was carried out on 209 children (107 healthy controls, 41 who were overweight and 61 with obesity) between 6 and 16 years of age. Mature RBC membrane phospholipids were analyzed for FA composition by gas chromatography-mass spectrometry (GC-MS). Dietary habits were evaluated using validated food frequency questionnaires (FFQ) and the Mediterranean Diet Quality Index for children (KIDMED) test. Compared to children with normal weight, children with obesity showed an inflammatory profile in mature RBC FAs, evidenced by higher levels of ω-6 polyunsaturated FAs (mainly arachidonic acid,

Indexed as

AdolescentBiomarkersChildErythrocyte MembraneFatty AcidsFatty Acids, MonounsaturatedFatty Acids, Omega-6Feeding BehaviorFemaleHumansMaleOverweightPediatric ObesityPhospholipidsRetrospective StudiesSpainBiomarkersFatty AcidsFatty Acids, MonounsaturatedFatty Acids, Omega-6Phospholipidschildhood obesityinflammationmembrane lipidomeomega-6 fatty acidsred blood cell

Identifiers

PMID33182783
PMCPMC7696547

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.